Minor groove hydrogen bonds and the replication of unnatural base pairs
about
Amplification, mutation, and sequencing of a six-letter synthetic genetic systemSubstitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin,Solution Structure, Mechanism of Replication, and Optimization of an Unnatural Base PairDiscovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet.Optimization of an unnatural base pair toward natural-like replicationSystematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabetMajor groove derivatization of an unnatural base pair.Quantifying the energetic contributions of desolvation and π-electron density during translesion DNA synthesis.Unnatural substrate repertoire of A, B, and X family DNA polymerases.Replication of a universal nucleobase provides unique insight into the role of entropy during DNA polymerization and pyrophosphorolysis.Synthetic nucleotides as probes of DNA polymerase specificity.Model systems for understanding DNA base pairing.The expanded genetic alphabet.Bromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases.Expanding the scope of replicable unnatural DNA: stepwise optimization of a predominantly hydrophobic base pair.Major groove substituents and polymerase recognition of a class of predominantly hydrophobic unnatural base pairs.Non-natural nucleotides as probes for the mechanism and fidelity of DNA polymerases.DNA interstrand cross-linking upon irradiation of aryl halide C-nucleotides.Site-specific labeling of DNA and RNA using an efficiently replicated and transcribed class of unnatural base pairs.Alternative DNA base-pairs: from efforts to expand the genetic code to potential material applications.In Vivo Structure-Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism.Synthetic Biology Parts for the Storage of Increased Genetic Information in Cells.Evolving a polymerase for hydrophobic base analogues.Expansion of the Genetic Alphabet: A Chemist's Approach to Synthetic Biology.2-Substituted dATP Derivatives as Building Blocks for Polymerase-Catalyzed Synthesis of DNA Modified in the Minor Groove.
P2860
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P2860
Minor groove hydrogen bonds and the replication of unnatural base pairs
description
2007 nî lūn-bûn
@nan
2007年の論文
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2007年論文
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2007年論文
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2007年論文
@zh-hk
2007年論文
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2007年論文
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2007年论文
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2007年论文
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2007年论文
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name
Minor groove hydrogen bonds and the replication of unnatural base pairs
@en
type
label
Minor groove hydrogen bonds and the replication of unnatural base pairs
@en
prefLabel
Minor groove hydrogen bonds and the replication of unnatural base pairs
@en
P2093
P2860
P356
P1476
Minor groove hydrogen bonds and the replication of unnatural base pairs
@en
P2093
Aaron M Leconte
Floyd E Romesberg
Shigeo Matsuda
P2860
P304
P356
10.1021/JA068282B
P407
P577
2007-04-06T00:00:00Z