Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling.
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Cholinergic agonists regulate JAK2/STAT3 signaling to suppress endothelial cell activationPivotal Importance of STAT3 in Protecting the Heart from Acute and Chronic Stress: New Advancement and Unresolved IssuesAcyloxy nitroso compounds inhibit LIF signaling in endothelial cells and cardiac myocytes: evidence that STAT3 signaling is redox-sensitiveLayered functional network analysis of gene expression in human heart failureDeciphering STAT3 signaling in the heart: plasticity and vascular inflammation.Activation of host tissue trophic factors through JAK-STAT3 signaling: a mechanism of mesenchymal stem cell-mediated cardiac repair.Expanding role of cyclin dependent kinases in cytokine inducible gene expression.Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart.Anti-Fibrotic Effects of Class I HDAC Inhibitor, Mocetinostat Is Associated with IL-6/Stat3 Signaling in Ischemic Heart Failure.Calyculin A reveals serine/threonine phosphatase protein phosphatase 1 as a regulatory nodal point in canonical signal transducer and activator of transcription 3 signaling of human microvascular endothelial cells.Selenate enhances STAT3 transcriptional activity in endothelial cells: differential actions of selenate and selenite on LIF cytokine signaling and cell viabilityPressure overload-induced cardiac remodeling and dysfunction in the absence of interleukin 6 in miceDepletion of cellular glutathione modulates LIF-induced JAK1-STAT3 signaling in cardiac myocytes.Berberine protects rat heart from ischemia/reperfusion injury via activating JAK2/STAT3 signaling and attenuating endoplasmic reticulum stress.Differential STAT3 signaling in the heart: Impact of concurrent signals and oxidative stress.Role of STAT3 in angiotensin II-induced hypertension and cardiac remodeling revealed by mice lacking STAT3 serine 727 phosphorylation.LIF and the heart: just another brick in the wall?A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells.IL-6 loss causes ventricular dysfunction, fibrosis, reduced capillary density, and dramatically alters the cell populations of the developing and adult heart.Cardiac STAT3 Deficiency Impairs Contractility and Metabolic Homeostasis in Hypertension.Leptin signaling in the failing and mechanically unloaded human heart.Roles of IL-6-gp130 Signaling in Vascular Inflammation.JAK redux: a second look at the regulation and role of JAKs in the heart.hSulf-1 inhibits cell proliferation and migration and promotes apoptosis by suppressing stat3 signaling in hepatocellular carcinoma.STAT3 and cardiac remodeling.When are pro-inflammatory cytokines SAFE in heart failure?Cardiotrophin-1 in hypertensive heart disease.Dancing rhinos in stilettos: The amazing saga of the genomic and nongenomic actions of STAT3 in the heart.Understanding STAT3 signaling in cardiac ischemia.IL-6 Activates PI3K and PKCζ Signaling and Determines Cardiac Differentiation in Rat Embryonic H9c2 Cells.The role of interleukin-6 in the formation of the coronary vasculature.Effect of adenovirus mediated β2-AR overexpression on IL-10 level secreted by cardiomyocytes of heart failure ratsInnate immunity and remodelling.Interplay between SAFE and RISK pathways in sphingosine-1-phosphate-induced cardioprotection.Endothelial fibrosis induced by suppressed STAT3 expression mediated by signaling involving the TGF-β1/ALK5/Smad pathway.Genetic deletion of the adaptor protein p66Shc increases susceptibility to short-term ischaemic myocardial injury via intracellular salvage pathways.STAT3α interacts with nuclear GSK3beta and cytoplasmic RISK pathway and stabilizes rhythm in the anoxic-reoxygenated embryonic heart.Regulation of JAK/STAT signalling by SOCS in the myocardium.Impaired JAK2-induced activation of STAT3 in failing human myocytes.
P2860
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P2860
Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Can the protective actions of ...... kin-6-type cytokine signaling.
@en
type
label
Can the protective actions of ...... kin-6-type cytokine signaling.
@en
prefLabel
Can the protective actions of ...... kin-6-type cytokine signaling.
@en
P1476
Can the protective actions of ...... kin-6-type cytokine signaling.
@en
P2093
George W Booz
Mazen Kurdi
P304
P356
10.1097/FJC.0B013E318068DD49
P577
2007-08-01T00:00:00Z