Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture.
about
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts.RNA interference for improving the outcome of islet transplantation.β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition.Accumulation of intrahepatic islet amyloid in a nonhuman primate transplant modelStress and the inflammatory process: a major cause of pancreatic cell death in type 2 diabetes.Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2.Ceramide formation as a target in beta-cell survival and function.Amyloid formation disrupts the balance between interleukin-1β and interleukin-1 receptor antagonist in human islets.TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook.Inhibition of glycosaminoglycan-mediated amyloid formation by islet amyloid polypeptide and proIAPP processing intermediates.Current and future treatment of amyloid diseases.Modulation of apoptosis pathways by oxidative stress and autophagy in β cells.Dual role of interleukin-1β in islet amyloid formation and its β-cell toxicity: Implications for type 2 diabetes and islet transplantation.Amyloid formation reduces protein kinase B phosphorylation in primary islet β-cells which is improved by blocking IL-1β signaling.Anakinra Protects Against Serum Deprivation-Induced Inflammation and Functional Derangement in Islets Isolated From Nonhuman Primates.The glucagon-like peptide-1 receptor agonist exenatide restores impaired pro-islet amyloid polypeptide processing in cultured human islets: implications in type 2 diabetes and islet transplantation.
P2860
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P2860
Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Small interfering RNA-mediated ...... al of human islets in culture.
@en
type
label
Small interfering RNA-mediated ...... al of human islets in culture.
@en
prefLabel
Small interfering RNA-mediated ...... al of human islets in culture.
@en
P2093
P2860
P356
P1433
P1476
Small interfering RNA-mediated ...... al of human islets in culture.
@en
P2093
C Bruce Verchere
Jose Oberholzer
Lawrence Rosenberg
Lucy Marzban
Paul E Fraser
Philippe A Halban
Thomas C Becker
P2860
P304
P356
10.2337/DB08-0485
P407
P577
2008-08-11T00:00:00Z