LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease.
about
Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging.Genetic insights into sporadic Parkinson's disease pathogenesis.Prediction of the repeat domain structures and impact of parkinsonism-associated variations on structure and function of all functional domains of leucine-rich repeat kinase 2 (LRRK2).LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2.Models of LRRK2-Associated Parkinson's Disease.68 and FX2149 Attenuate Mutant LRRK2-R1441C-Induced Neural Transport Impairment.Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson's disease.Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease.Modeling Parkinson's Disease in Drosophila: What Have We Learned for Dominant Traits?
P2860
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P2860
LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease.
@en
type
label
LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease.
@en
prefLabel
LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease.
@en
P2860
P356
P1476
LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease.
@en
P2093
Valina L Dawson
Yulan Xiong
P2860
P304
P356
10.1042/BST20120093
P577
2012-10-01T00:00:00Z