Multiple steps determine the overall rate of the reduction of 5alpha-dihydrotestosterone catalyzed by human type 3 3alpha-hydroxysteroid dehydrogenase: implications for the elimination of androgens.
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The syndrome of 17,20 lyase deficiencyWhy boys will be boys: two pathways of fetal testicular androgen biosynthesis are needed for male sexual differentiationIdentification of the molecular switch that regulates access of 5alpha-DHT to the androgen receptorAndrogen biosynthesis in castration-resistant prostate cancerCatalytic mechanism and substrate specificity of the beta-subunit of the voltage-gated potassium channelHuman aldo-keto reductases and the metabolic activation of polycyclic aromatic hydrocarbonsModeling single nucleotide polymorphisms in the human AKR1C1 and AKR1C2 genes: implications for functional and genotyping analyses.Characterization of disease-related 5beta-reductase (AKR1D1) mutations reveals their potential to cause bile acid deficiency.New frontiers in androgen biosynthesis and metabolism.Rate of steroid double-bond reduction catalysed by the human steroid 5β-reductase (AKR1D1) is sensitive to steroid structure: implications for steroid metabolism and bile acid synthesisMetabolism of the synthetic progestogen norethynodrel by human ketosteroid reductases of the aldo-keto reductase superfamilyRole of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolismSteroid hormone transforming aldo-keto reductases and cancer.Human aldo-keto reductases: Function, gene regulation, and single nucleotide polymorphisms.Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1)Human hydroxysteroid dehydrogenases and pre-receptor regulation: insights into inhibitor design and evaluation.Promiscuity and diversity in 3-ketosteroid reductases.Biological role of aldo-keto reductases in retinoic Acid biosynthesis and signaling.Oxidation of dihydrotestosterone by human cytochromes P450 19A1 and 3A4.In-Depth Dissection of the P133R Mutation in Steroid 5β-Reductase (AKR1D1): A Molecular Basis of Bile Acid DeficiencyPre-receptor regulation of the androgen receptor5β-Reduced steroids and human Δ(4)-3-ketosteroid 5β-reductase (AKR1D1).Gonadal steroid hormones and the hypothalamo-pituitary-adrenal axis.Human aldo-keto reductases: structure, substrate specificity and roles in tumorigenesis.Single-molecule enzymology of steroid transforming enzymes: Transient kinetic studies and what they tell us.Androgen deprivation promotes intratumoral synthesis of dihydrotestosterone from androgen metabolites in prostate cancer.Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone.The rate-determining steps of aldo-keto reductases (AKRs), a study on human steroid 5β-reductase (AKR1D1).Kinetics of nucleotide binding to the beta-subunit (AKR6A2) of the voltage-gated potassium (Kv) channel.The aldo-keto reductase superfamily and its role in drug metabolism and detoxification
P2860
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P2860
Multiple steps determine the overall rate of the reduction of 5alpha-dihydrotestosterone catalyzed by human type 3 3alpha-hydroxysteroid dehydrogenase: implications for the elimination of androgens.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2006
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Multiple steps determine the o ...... the elimination of androgens.
@en
Multiple steps determine the o ...... the elimination of androgens.
@nl
type
label
Multiple steps determine the o ...... the elimination of androgens.
@en
Multiple steps determine the o ...... the elimination of androgens.
@nl
prefLabel
Multiple steps determine the o ...... the elimination of androgens.
@en
Multiple steps determine the o ...... the elimination of androgens.
@nl
P2860
P356
P1433
P1476
Multiple steps determine the o ...... the elimination of androgens.
@en
P2093
Trevor M Penning
P2860
P304
13054-13063
P356
10.1021/BI060591R
P407
P577
2006-10-01T00:00:00Z