Iterative in situ click chemistry creates antibody-like protein-capture agents. - Wikidata - thesis-toulmin - TriplyDB

Iterative in situ click chemistry creates antibody-like protein-capture agents.

Iterative in situ click chemistry creates antibody-like protein-capture agents.

http://www.wikidata.org/entity/Q37027473

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High-Q optical sensors for chemical and biological analysis.In situ click chemistry: from small molecule discovery to synthetic antibodies Kinetic target-guided synthesis in drug discovery and chemical biology: a comprehensive facts and figures survey Approaches to Validate and Manipulate RNA Targets with Small Molecules in Cells A versatile approach to transform low-affinity peptides into protein probes with cotranslationally expressed chemical cross-linker.Rapid identification of improved protein ligands using peptoid microarrays Aptamers and the next generation of diagnostic reagents.Water-driven ligations using cyclic amino squarates: a class of useful SN1-like reactions.A chemical epitope-targeting strategy for protein capture agents: the serine 474 epitope of the kinase Akt2.Screening of protein-protein interaction modulators via sulfo-click kinetic target-guided synthesis Strategic workshops on cancer nanotechnology Investigating fluorescent dyes in fluorescence-assisted screenings.Turning single cells into microarrays by super-resolution barcoding.Programmable nano-bio-chips: multifunctional clinical tools for use at the point-of-care.Evaluation of phage display discovered peptides as ligands for prostate-specific membrane antigen (PSMA).A cocktail of thermally stable, chemically synthesized capture agents for the efficient detection of anti-gp41 antibodies from human sera 1,3-Dipolar cycloaddition reactivities of perfluorinated aryl azides with enamines and strained dipolarophiles A protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH domain of Akt1.A General Synthetic Approach for Designing Epitope Targeted Macrocyclic Peptide Ligands Identification of selective covalent inhibitors of platelet activating factor acetylhydrolase 1B2 from the screening of an oxadiazolone-capped peptoid-azapeptoid hybrid library.An efficient strategy to enhance binding affinity and specificity of a known isozyme inhibitor Protein catalyzed capture agents with tailored performance for in vitro and in vivo applications.Single-cell systems biology by super-resolution imaging and combinatorial labeling.Combinatorial chemistry in drug discovery.Iterative in situ click chemistry assembles a branched capture agent and allosteric inhibitor for Akt1.Degradation of Akt using protein-catalyzed capture agents.DNA sequencing methods in human genetics and disease research.New and improved proteomics technologies for understanding complex biological systems: addressing a grand challenge in the life sciences.Synthetic receptors with antibody-like binding affinities.Precise synthesis of molecularly defined oligomers and polymers by orthogonal iterative divergent/convergent approaches.Bioorthogonal labelling of biomolecules: new functional handles and ligation methods.Multiplexed evaluation of capture agent binding kinetics using arrays of silicon photonic microring resonators.New insights into the kinetic target-guided synthesis of protein ligands.Ribosome-Templated Azide-Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry.Chemically synthesized molecules with the targeting and effector functions of antibodies.Probing the binding site of abl tyrosine kinase using in situ click chemistry.Target guided synthesis using DNA nano-templates for selectively assembling a G-quadruplex binding c-MYC inhibitor.Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry.Grand challenge commentary: Informative diagnostics for personalized medicine.Alkyne-azide click reaction catalyzed by metallic copper under ultrasound.

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P2860

Iterative in situ click chemistry creates antibody-like protein-capture agents.

http://www.wikidata.org/entity/Q37027473

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on January 2009

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

Iterative in situ click chemistry creates antibody-like protein-capture agents.

@en

Iterative in situ click chemistry creates antibody-like protein-capture agents.

@nl

type

label

Iterative in situ click chemistry creates antibody-like protein-capture agents.

@en

Iterative in situ click chemistry creates antibody-like protein-capture agents.

@nl

prefLabel

Iterative in situ click chemistry creates antibody-like protein-capture agents.

@en

Iterative in situ click chemistry creates antibody-like protein-capture agents.

@nl

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Angewandte Chemie International Edition

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Iterative in situ click chemistry creates antibody-like protein-capture agents.

@en

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Abdul Ahad Tariq

http://www.w3.org/2001/XMLSchema#string

Arundhati Nag

http://www.w3.org/2001/XMLSchema#string

Heather D Agnew

http://www.w3.org/2001/XMLSchema#string

James R Heath

http://www.w3.org/2001/XMLSchema#string

Jason E Hein

http://www.w3.org/2001/XMLSchema#string

Rosemary D Rohde

http://www.w3.org/2001/XMLSchema#string

Russell J Krom

http://www.w3.org/2001/XMLSchema#string

Steven W Millward

http://www.w3.org/2001/XMLSchema#string

Suresh M Pitram

http://www.w3.org/2001/XMLSchema#string

Vanessa M Burns

http://www.w3.org/2001/XMLSchema#string

P2860

Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

The "One-Bead-One-Compound" Combinatorial Library Method.

Isolation of protein ligands from large peptoid libraries.

Transformation of low-affinity lead compounds into high-affinity protein capture agents.

Synthetic molecules as antibody replacements.

Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity.

Automated selection of aptamers against protein targets translated in vitro: from gene to aptamer.

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4944-4948

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scholarly article

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10.1002/ANIE.200900488

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P433

27

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48

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Karl Barry Sharpless

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2009-01-01T00:00:00Z

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24215044

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19301344

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3716464

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