The role of Dickkopf-1 in bone development, homeostasis, and disease
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Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune DiseasesImpact of inflammation on the osteoblast in rheumatic diseasesProteomics approaches for the studies of bone metabolismCrystal structures of the extracellular domain of LRP6 and its complex with DKK1Structures and mechanism for the design of highly potent glucocorticoidsRoles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cellsComputational modeling of interactions between multiple myeloma and the bone microenvironmentGenetic evidence that SOST inhibits WNT signaling in the limbDickkopf-1 regulates bone formation in young growing rodents and upon traumatic injuryGeneration and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivoIncrease in Dickkopf-1 Serum Level in Recent Spondyloarthritis. Data from the DESIR Cohort.Increased Dickkopf-1 in Recent-onset Rheumatoid Arthritis is a New Biomarker of Structural Severity. Data from the ESPOIR CohortNegative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2.Receptor activator of nuclear factor kappa-B ligand (RANKL) but not sclerostin or gene polymorphisms is related to joint destruction in early rheumatoid arthritis.Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic HipsDecreased Circulating Levels of Dickkopf-1 in Patients with Exudative Age-related Macular DegenerationOsteoblastogenesis and tumor growth in myeloma.Bone mineral density and serum biochemical predictors of bone loss in patients with CKD on dialysis.Human Dickkopf-1 (huDKK1) protein: characterization of glycosylation and determination of disulfide linkages in the two cysteine-rich domains.Dickkopf-1 is a key regulator of myeloma bone disease: opportunities and challenges for therapeutic interventionTranscriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myelomaWnt-related molecules and signaling pathway equilibrium in hematopoiesis.Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastasesSclerostin and Dickkopf-1 in renal osteodystrophy.Characterization of the molecular mechanism of the bone-anabolic activity of carfilzomib in multiple myeloma.Serum Dickkopf-1 signaling and calcium deposition in aortic valve are significantly related to the presence of concomitant coronary atherosclerosis in patients with symptomatic calcified aortic stenosisConstitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development.Investigation of inflammation and tissue patterning in the gut using a Spatially Explicit General-purpose Model of Enteric Tissue (SEGMEnT).Molecular changes in pre-metastatic lymph nodes of esophageal cancer patients.Bone healing: little secrets.The PCa Tumor Microenvironment.Wnt/Β-catenin and sex hormone signaling in endometrial homeostasis and cancer.Dickkopf1: a tumor suppressor or metastasis promoter?Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin.The Wnt inhibitor dickkopf-1: a link between breast cancer and bone metastases.Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis.Update on Wnt signaling in bone cell biology and bone disease.High Parathyroid Hormone Level and Osteoporosis Predict Progression of Coronary Artery Calcification in Patients on Dialysis.Effects of Combined Exposure to Lead and High-Fat Diet on Bone Quality in Juvenile Male MiceCalycosin-7-O-β-d-glucopyranoside stimulates osteoblast differentiation through regulating the BMP/WNT signaling pathways
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The role of Dickkopf-1 in bone development, homeostasis, and disease
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 07 August 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The role of Dickkopf-1 in bone development, homeostasis, and disease
@en
The role of Dickkopf-1 in bone development, homeostasis, and disease.
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type
label
The role of Dickkopf-1 in bone development, homeostasis, and disease
@en
The role of Dickkopf-1 in bone development, homeostasis, and disease.
@nl
prefLabel
The role of Dickkopf-1 in bone development, homeostasis, and disease
@en
The role of Dickkopf-1 in bone development, homeostasis, and disease.
@nl
P2093
P2860
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P1476
The role of Dickkopf-1 in bone development, homeostasis, and disease
@en
P2093
Brett M Hall
John D Shaughnessy
Joseph J Pinzone
Martin Vonau
Nanda K Thudi
P2860
P304
P356
10.1182/BLOOD-2008-03-145169
P407
P577
2008-08-07T00:00:00Z