Switch 1 mutation S217A converts myosin V into a low duty ratio motor
about
Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neuronsMyosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon developmentCoarse-grained simulation of myosin-V movement.Functional adaptation of the switch-2 nucleotide sensor enables rapid processive translocation by myosin-5.MYO1E mutations and childhood familial focal segmental glomerulosclerosis.Coupling of two non-processive myosin 5c dimers enables processive stepping along actin filaments.The kinetic mechanism of mouse myosin VIIAA hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity.Drosophila melanogaster myosin-18 represents a highly divergent motor with actin tethering propertiesSwitch II mutants reveal coupling between the nucleotide- and actin-binding regions in myosin V.A branched kinetic scheme describes the mechanochemical coupling of Myosin Va processivity in response to substrate.Structural basis for drug-induced allosteric changes to human β-cardiac myosin motor activityThe SAH domain extends the functional length of the myosin leverHow actin initiates the motor activity of MyosinMyosin-Va and dynamic actin oppose microtubules to drive long-range organelle transport.The Shaker-1 Mouse Myosin VIIa Deafness Mutation Results in a Severely Reduced Rate of the ATP Hydrolysis Step.Kinetic signatures of myosin-5B, the motor involved in microvillus inclusion disease.Distinct sites in tropomyosin specify shared and isoform-specific regulation of myosins II and V.
P2860
Q28507993-89923BFC-C03C-427A-8C85-4ABA318BCE18Q28577414-EA98884A-5019-4270-B7C5-616E0D13ED52Q30417695-21A0E8BD-2EDF-4FA7-AE0D-36076426DC45Q30497272-051C95B5-F6A6-48BD-A248-53FB298E0DA9Q30541167-AF0139FC-0C69-4DF6-93C7-80DDB1B2D4E9Q33585953-E20B1119-CCAE-49A1-932A-1C4E083C7C7BQ34685505-ED599895-77F0-4F37-8AC6-331952DF4B50Q34687221-10F37A84-E068-42A3-AD05-AFAAA680AB2AQ35065264-9EC4E08B-32DC-4147-96D6-374EE3AE1088Q36010853-21C2363F-0D4F-49DF-BA42-DD7DC656930CQ36238156-E63FE155-30F9-4816-A759-DA189F591609Q37031923-DD13411B-551F-4341-8552-D2F18036D785Q37477144-7951C0E1-1A5C-4F44-AA1A-108FEE0CC5ABQ42412794-1BC11B19-6B86-479C-901E-F093189C29C6Q42787767-3745C673-6AAA-44A0-8468-93E2666E5D02Q45073728-F6529982-4F39-42EE-BED5-EF069DA1AA2FQ47695282-62F37F41-6E3F-4399-A7FE-9C7E2E0767AEQ52676165-A67436DB-7C4A-4B4E-A039-ED774A9A6AE8
P2860
Switch 1 mutation S217A converts myosin V into a low duty ratio motor
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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name
Switch 1 mutation S217A converts myosin V into a low duty ratio motor
@en
Switch 1 mutation S217A converts myosin V into a low duty ratio motor.
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type
label
Switch 1 mutation S217A converts myosin V into a low duty ratio motor
@en
Switch 1 mutation S217A converts myosin V into a low duty ratio motor.
@nl
prefLabel
Switch 1 mutation S217A converts myosin V into a low duty ratio motor
@en
Switch 1 mutation S217A converts myosin V into a low duty ratio motor.
@nl
P2093
P2860
P356
P1476
Switch 1 mutation S217A converts myosin V into a low duty ratio motor
@en
P2093
Betty Belknap
Eva Forgacs
Howard D White
James R Sellers
Judit Tóth
Suzanne Cartwright
Takeshi Sakamoto
P2860
P304
P356
10.1074/JBC.M805530200
P407
P577
2008-11-12T00:00:00Z