Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death.
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The evolving role of nonsteroidal anti-inflammatory drugs in colon cancer prevention: a cause for optimismPhospho-aspirin-2 (MDC-22) inhibits estrogen receptor positive breast cancer growth both in vitro and in vivo by a redox-dependent effectDanthron triggers ROS and mitochondria-mediated apoptotic death in C6 rat glioma cells through caspase cascades, apoptosis-inducing factor and endonuclease G multiple signaling.In vitro evaluation of novel N-acetylalaninate prodrugs that selectively induce apoptosis in prostate cancer cellsChemotherapeutic properties of phospho-nonsteroidal anti-inflammatory drugs, a new class of anticancer compounds.Effect of marine omega 3 fatty acids on methylmercury-induced toxicity in fish and mammalian cells in vitro.Phospho-ibuprofen (MDC-917) suppresses breast cancer growth: an effect controlled by the thioredoxin system.The Antineoplastic Effect of Nitric Oxide-Donating Acetylsalicylic Acid (NO-ASA) in Chronic Lymphocytic Leukemia (CLL) Cells is Highly Dependent on its Positional Isomerism.Effects of Nrf2 silencing on oxidative stress-associated intestinal carcinogenesis in mice.Phosphoaspirin (MDC-43), a novel benzyl ester of aspirin, inhibits the growth of human cancer cell lines more potently than aspirin: a redox-dependent effect.Inhibitory effect of trans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instabilitySulindac metabolism and synergy with tumor necrosis factor-alpha in a drug-inflammation interaction model of idiosyncratic liver injury.Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations.Dietary flavonoids as cancer prevention agents.New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin.The proapoptotic effect of traditional and novel nonsteroidal anti-inflammatory drugs in mammalian and yeast cells.Protein nitration and nitrosylation by NO-donating aspirin in colon cancer cells: Relevance to its mechanism of action.Hitting the Bull's-Eye in Metastatic Cancers-NSAIDs Elevate ROS in Mitochondria, Inducing Malignant Cell Death.Nitric Oxide-Releasing Aspirin Suppresses NF-κB Signaling in Estrogen Receptor Negative Breast Cancer Cells in Vitro and in Vivo.The hexacarbonyldicobalt derivative of aspirin acts as a CO-releasing NSAID on malignant mesothelioma cells.Cyclooxygenase-2/prostaglandin E₂ inducing effects of α-tocopheryl polyethylene glycol succinate in lung epithelial cells.The effects of nepafenac and amfenac on retinal angiogenesis.Improved Antitumor Activity of a Therapeutic Melanoma Vaccine through the Use of the Dual COX-2/5-LO Inhibitor LicofeloneExtract of Ginkgo biloba exacerbates liver metastasis in a mouse colon cancer Xenograft model.Protein kinase CK2 regulates redox homeostasis through NF-κB and Bcl-xL in cardiomyoblasts.Efficacy of acetylsalicylic acid (aspirin) in skin B16-F0 melanoma tumor-bearing C57BL/6 mice.TGF-β1 mediates the effects of aspirin on colonic tumor cell proliferation and apoptosis.
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Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 24 October 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Chemopreventive agents induce ...... COX-2-independent cell death.
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Chemopreventive agents induce ...... COX-2-independent cell death.
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type
label
Chemopreventive agents induce ...... COX-2-independent cell death.
@en
Chemopreventive agents induce ...... COX-2-independent cell death.
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prefLabel
Chemopreventive agents induce ...... COX-2-independent cell death.
@en
Chemopreventive agents induce ...... COX-2-independent cell death.
@nl
P2093
P2860
P356
P1433
P1476
Chemopreventive agents induce ...... COX-2-independent cell death.
@en
P2093
P2860
P304
P356
10.1093/CARCIN/BGN242
P407
P577
2008-10-24T00:00:00Z