Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principle
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Bioanalysis of eukaryotic organellesMitochondrial targeting of mouse NQO1 and CYP1B1 proteinsLow-dose synergistic immunosuppression of T-dependent antibody responses by polycyclic aromatic hydrocarbons and arsenic in C57BL/6J murine spleen cellsCytochrome P450 CYP1A1: wider roles in cancer progression and prevention.Mitochondrial activity and oxidative stress functions are influenced by the activation of AhR-induced CYP1A1 overexpression in cardiomyocytes.A global view of porcine transcriptome in three tissues from a full-sib pair with extreme phenotypes in growth and fat deposition by paired-end RNA sequencing.Organ-specific roles of CYP1A1 during detoxication of dietary benzo[a]pyrene.Mitochondria-targeted cytochrome P450 2E1 induces oxidative damage and augments alcohol-mediated oxidative stress.Bimodal targeting of microsomal cytochrome P450s to mitochondria: implications in drug metabolism and toxicityBimodal targeting of cytochrome P450s to endoplasmic reticulum and mitochondria: the concept of chimeric signals.Overexpression of Catalase Enhances Benzo(a)pyrene Detoxification in Endothelial Microsomes.Human cytochromes P450 in health and diseaseMetabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease.Human cytochrome P450 2E1 mutations that alter mitochondrial targeting efficiency and susceptibility to ethanol-induced toxicity in cellular models.Mitochondria as a target of environmental toxicants.Comprehensive analysis of genetic variations in strictly-defined Leber congenital amaurosis with whole-exome sequencing in Chinese.Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction.Emerging roles for brain drug-metabolizing cytochrome P450 enzymes in neuropsychiatric conditions and responses to drugs.Aryl hydrocarbon receptor ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin enhances liver damage in bile duct-ligated mice.Identification of mitochondrial cytochrome P450 induced in response to polycyclic aromatic hydrocarbons in the mummichog (Fundulus heteroclitus).β-Naphthoflavone-Induced Mitochondrial Respiratory Damage in Cyp1 Knockout Mouse and in Cell Culture Systems: Attenuation by Resveratrol Treatment.Clinical effects of chemical exposures on mitochondrial function.
P2860
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P2860
Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principle
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Knock-in mouse lines expressin ...... a]pyrene as proof of principle
@en
Knock-in mouse lines expressin ...... ]pyrene as proof of principle.
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type
label
Knock-in mouse lines expressin ...... a]pyrene as proof of principle
@en
Knock-in mouse lines expressin ...... ]pyrene as proof of principle.
@nl
prefLabel
Knock-in mouse lines expressin ...... a]pyrene as proof of principle
@en
Knock-in mouse lines expressin ...... ]pyrene as proof of principle.
@nl
P2093
P2860
P356
P1476
Knock-in mouse lines expressin ...... a]pyrene as proof of principle
@en
P2093
Daniel W Nebert
Hongbin Dong
Howard G Shertzer
Marian L Miller
Narayan G Avadhani
Seema Bansal
Shigeyuki Uno
Timothy P Dalton
Zhanquan Shi
P2860
P304
P356
10.1124/MOL.108.051888
P577
2008-12-01T00:00:00Z