Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase - Wikidata - thesis-toulmin - TriplyDB

Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase

Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase

http://www.wikidata.org/entity/Q37294374

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Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer Modulators affecting the immune dialogue between human immune and colon cancer cells Simvastatin, an HMG-CoA reductase inhibitor, exhibits anti-metastatic and anti-tumorigenic effects in endometrial cancer Statin therapy is associated with improved survival in patients with non-serous-papillary epithelial ovarian cancer: a retrospective cohort analysis.Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells.Comparison of clinical outcomes of hydrophilic and lipophilic statins in patients with acute myocardial infarction Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells.Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study.Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells.The HMG-CoA reductase inhibitor, simvastatin, exhibits anti-metastatic and anti-tumorigenic effects in ovarian cancer Effect of pravastatin on the survival of patients with advanced gastric cancer.Lovastatin causes FaDu hypopharyngeal carcinoma cell death via AMPK-p63-survivin signaling cascade HMG-CoA reductase inhibitors (statins) use and risk of non-Hodgkin lymphoma in HIV-positive persons.Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer.Caveolae as a target to quench autoinduction of the metastatic phenotype in lung cancer.Targeting Cancer Metabolism: Dietary and Pharmacologic Interventions.Statin use and uterine fibroid risk in hyperlipidemia patients: a nested case-control study.Statin use and endometrial cancer risk: a meta-analysis.Protective effects of coenzyme Q10 and L-carnitine against statin-induced pancreatic mitochondrial toxicity in rats.Lovastatin induced Kruppel like factor 2 (KLF2), Kruppel like factor 6 (KLF6) and Ras homolog family member B (RHOB) genes and preferentially led to viability reduction of Cisplatin-resistant cells.Differences of statin activity in 2D and 3D pancreatic cancer cell cultures.The impact on high-grade serous ovarian cancer of obesity and lipid metabolism-related gene expression patterns: the underestimated driving force affecting prognosis.ABT-737 and pictilisib synergistically enhance pitavastatin-induced apoptosis in ovarian cancer cells.Melatonin potentiates the anti-tumour effect of pravastatin in rat mammary gland carcinoma model.The role of atorvastatin in suppressing tumor growth of uterine fibroids.Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters

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Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase

http://www.wikidata.org/entity/Q37294374

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 11 May 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Lipophilic but not hydrophilic ...... igh levels of HMGCoA reductase

@en

Lipophilic but not hydrophilic ...... gh levels of HMGCoA reductase.

@nl

type

label

Lipophilic but not hydrophilic ...... igh levels of HMGCoA reductase

@en

Lipophilic but not hydrophilic ...... gh levels of HMGCoA reductase.

@nl

prefLabel

Lipophilic but not hydrophilic ...... igh levels of HMGCoA reductase

@en

Lipophilic but not hydrophilic ...... gh levels of HMGCoA reductase.

@nl

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J.1582-4934.2009.00771.X

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Journal of Cellular and Molecular Medicine

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Lipophilic but not hydrophilic ...... igh levels of HMGCoA reductase

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A Sadarangani

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B Oliva

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G I Owen

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J Brañes

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J Carvajal

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K Chen-Lin

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M Cuello

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R Gejman

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S Kato

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S Smalley

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P2860

Synergistic interaction of lovastatin and paclitaxel in human cancer cells

GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors

p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases.

Characterization of a clonal isolate of an oxaliplatin resistant ovarian carcinoma cell line A2780/C10.

Pharmacological effects of HMG CoA reductase inhibitors other than lipoprotein modulation.

Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors.

Therapy insight: Potential of statins for cancer chemoprevention and therapy.

Statin use and female reproductive organ cancer risk in a large population-based setting.

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1180-1193

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scholarly article

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10.1111/J.1582-4934.2009.00771.X

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5

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