Characterization and interlaboratory comparison of a gene expression signature for differentiating genotoxic mechanisms.
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Synergistic Gene Expression Signature Observed in TK6 Cells upon Co-Exposure to UVC-Irradiation and Protein Kinase C-Activating Tumor PromotersApplication of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.The Salmonella mutagenicity assay: the stethoscope of genetic toxicology for the 21st century.The evolution of bioinformatics in toxicology: advancing toxicogenomicsGenetic toxicology in the 21st century: reflections and future directions.Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells.Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cellsIdentification of Stage-Specific Gene Expression Signatures in Response to Retinoic Acid during the Neural Differentiation of Mouse Embryonic Stem Cells.Gene and protein analysis reveals that p53 pathway is functionally inactivated in cytogenetically normal Acute Myeloid Leukemia and Acute Promyelocytic LeukemiaHepatic mRNA, microRNA, and miR-34a-target responses in mice after 28 days exposure to doses of benzo(a)pyrene that elicit DNA damage and mutationA Microchip for Integrated Single-Cell Gene Expression Profiling and Genotoxicity Detection.Tuning the metabolism of the anticancer drug cisplatin with chemoprotective agents to improve its safety and efficacy.A metabolomics investigation of non-genotoxic carcinogenicity in the rat.Opportunities for an alternative integrating testing strategy for carcinogen hazard assessment?The impact of DNA methylation technologies on drug toxicology.Cell-based biosensor to report DNA damage in micro- and nanosystems.Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicityCharacterization of formaldehyde's genotoxic mode of action by gene expression analysis in TK6 cells.Validation of Transcriptomics-Based In Vitro Methods.A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.Evaluation of vitamin B12 effects on DNA damage induced by paclitaxel.An integrative test strategy for cancer hazard identification.Replication-dependent histone isoforms: a new source of complexity in chromatin structure and function
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P2860
Characterization and interlaboratory comparison of a gene expression signature for differentiating genotoxic mechanisms.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Characterization and interlabo ...... ntiating genotoxic mechanisms.
@en
Characterization and interlabo ...... ntiating genotoxic mechanisms.
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type
label
Characterization and interlabo ...... ntiating genotoxic mechanisms.
@en
Characterization and interlabo ...... ntiating genotoxic mechanisms.
@nl
prefLabel
Characterization and interlabo ...... ntiating genotoxic mechanisms.
@en
Characterization and interlabo ...... ntiating genotoxic mechanisms.
@nl
P2093
P2860
P356
P1476
Characterization and interlabo ...... ntiating genotoxic mechanisms.
@en
P2093
Anne-Celine Le Fevre
Catherine Spire
Chinami Aruga
Daniel Bauer
Donna Dickinson
Eric Boitier
Gotaro Tanaka
Heidrun Ellinger-Ziegelbauer
Jean-Christophe Hoflack
Jennifer M Fostel
P2860
P304
P356
10.1093/TOXSCI/KFP103
P577
2009-05-22T00:00:00Z