Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization.
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Calcium influx and male fertility in the context of the sperm proteome: an updateHuman PLCζ exhibits superior fertilization potency over mouse PLCζ in triggering the Ca(2+) oscillations required for mammalian oocyte activationSperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes.Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase Cζ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP2).Novel signalling mechanism and clinical applications of sperm-specific PLCζ.Oocyte activation deficiency: a role for an oocyte contribution?Antigen unmasking enhances visualization efficacy of the oocyte activation factor, phospholipase C zeta, in mammalian sperm.Oocyte Activation and Fertilisation: Crucial Contributors from the Sperm and Oocyte.Mutations in PLCδ1 associated with hereditary leukonychia display divergent PIP2 hydrolytic function.Calcium influx and sperm-evoked calcium responses during oocyte maturation and egg activation.Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation.PLCζ Induced Ca2+ Oscillations in Mouse Eggs Involve a Positive Feedback Cycle of Ca2+ Induced InsP3 Formation From Cytoplasmic PIP2.
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Chimeras of sperm PLCζ reveal disparate protein domain functions in the generation of intracellular Ca2+ oscillations in mammalian eggs at fertilization.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Chimeras of sperm PLCζ reveal ...... mmalian eggs at fertilization.
@en
Chimeras of sperm PLCζ reveal ...... mmalian eggs at fertilization.
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type
label
Chimeras of sperm PLCζ reveal ...... mmalian eggs at fertilization.
@en
Chimeras of sperm PLCζ reveal ...... mmalian eggs at fertilization.
@nl
prefLabel
Chimeras of sperm PLCζ reveal ...... mmalian eggs at fertilization.
@en
Chimeras of sperm PLCζ reveal ...... mmalian eggs at fertilization.
@nl
P2093
P2860
P50
P356
P1476
Chimeras of sperm PLCζ reveal ...... mmalian eggs at fertilization.
@en
P2093
Brian L Calver
George Nounesis
J Raul Gonzalez-Garcia
Karl Swann
Khalil Elgmati
Maria Theodoridou
Zili Sideratou
P2860
P304
P356
10.1093/MOLEHR/GAT070
P577
2013-10-23T00:00:00Z