Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance
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Galactic cosmic radiation leads to cognitive impairment and increased aβ plaque accumulation in a mouse model of Alzheimer's diseaseIn vivo imaging reveals sigmoidal growth kinetic of β-amyloid plaques.Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrineImaging of Leukocyte Trafficking in Alzheimer's DiseaseInnate immunity in Alzheimer's disease: a complex affairSorting through the roles of beclin 1 in microglia and neurodegenerationAltered morphological dynamics of activated microglia after induction of status epilepticus.An automated method to quantify microglia morphology and application to monitor activation state longitudinally in vivoMicroglia development and functionFunctional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathologyCCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunctionMicroglia communication: Parallels between aging and Alzheimer's diseaseNeuroinflammation in Alzheimer's diseaseSingle-walled carbon nanotubes alleviate autophagic/lysosomal defects in primary glia from a mouse model of Alzheimer's diseaseMicroglia as a critical player in both developmental and late-life CNS pathologies.Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions.Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice.Microfluidic chemotaxis platform for differentiating the roles of soluble and bound amyloid-β on microglial accumulation.Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease.Systemic inflammation regulates microglial responses to tissue damage in vivoComplement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microgliaAmelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer's disease model.Low energy laser light (632.8 nm) suppresses amyloid-β peptide-induced oxidative and inflammatory responses in astrocytes.Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.New insights on the role of microglia in synaptic pruning in health and diseaseNovel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses.In vivo characterization of a bigenic fluorescent mouse model of Alzheimer's disease with neurodegenerationLongitudinal in vivo two-photon fluorescence imaging.Decreased amyloid-β pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model miceProliferation in the Alzheimer hippocampus is due to microglia, not astroglia, and occurs at sites of amyloid deposition.Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial functionCX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.Measurements of multiphoton action cross sections for multiphoton microscopyHuman intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's diseaseToll-like receptors in health and disease in the brain: mechanisms and therapeutic potential.Toll-like receptors in Alzheimer's diseaseMicroglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks.A review of neuroimaging biomarkers of Alzheimer's disease.Pathology associated with AAV mediated expression of beta amyloid or C100 in adult mouse hippocampus and cerebellum
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Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance
@en
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance.
@nl
type
label
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance
@en
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance.
@nl
prefLabel
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance
@en
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance.
@nl
P2093
P2860
P50
P1476
Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance
@en
P2093
Chester A Mathis
Daniel Eicke
Michael E Calhoun
Rebecca Radde
Shinichi Kohsaka
Tristan Bolmont
P2860
P304
P356
10.1523/JNEUROSCI.4814-07.2008
P407
P577
2008-04-01T00:00:00Z