Fusion genes in solid tumors: an emerging target for cancer diagnosis and treatment
about
Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR DysregulationTargeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and TreatmentEmergence of FGFR family gene fusions as therapeutic targets in a wide spectrum of solid tumoursRecurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma.Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification.Topoisomerase IIα in chromosome instability and personalized cancer therapy.KAOS: a new automated computational method for the identification of overexpressed genes.ChimeRScope: a novel alignment-free algorithm for fusion transcript prediction using paired-end RNA-Seq data.FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review).Post-transcriptional regulatory network of epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions.Detecting and targetting oncogenic fusion proteins in the genomic era.Gaining comprehensive biological insight into the transcriptome by performing a broad-spectrum RNA-seq analysis.Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumoursGenetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma.Characterization of chromosomal translocation breakpoint sequences in solid tumours: "an in silico analysis".Strong FGFR3 staining is a marker for FGFR3 fusions in diffuse gliomas.FGFR3-TACC3 cancer gene fusions cause mitotic defects by removal of endogenous TACC3 from the mitotic spindleThe rationale for druggability of CCDC6-tyrosine kinase fusions in lung cancer.Fusions in solid tumours: diagnostic strategies, targeted therapy, and acquired resistance.Identification of novel cyclin gene fusion transcripts in endometrioid ovarian carcinomas.Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing.Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas.Merestinib (LY2801653) inhibits neurotrophic receptor kinase (NTRK) and suppresses growth of NTRK fusion bearing tumors.Transcriptomic and genomic profiling of early-stage ovarian carcinomas associated with histotype and overall survivalIndel sensitive and comprehensive variant/mutation detection from RNA sequencing data for precision medicinePatterns and mechanisms of structural variations in human cancer
P2860
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P2860
Fusion genes in solid tumors: an emerging target for cancer diagnosis and treatment
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
@wuu
2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
@zh-sg
2013年學術文章
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2013年學術文章
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2013年學術文章
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name
Fusion genes in solid tumors: an emerging target for cancer diagnosis and treatment
@en
Fusion genes in solid tumors: an emerging target for cancer diagnosis and treatment.
@nl
type
label
Fusion genes in solid tumors: an emerging target for cancer diagnosis and treatment
@en
Fusion genes in solid tumors: an emerging target for cancer diagnosis and treatment.
@nl
prefLabel
Fusion genes in solid tumors: an emerging target for cancer diagnosis and treatment
@en
Fusion genes in solid tumors: an emerging target for cancer diagnosis and treatment.
@nl
P2860
P356
P1476
Fusion genes in solid tumors: an emerging target for cancer diagnosis and treatment
@en
P2093
Brittany C Parker
P2860
P304
P356
10.5732/CJC.013.10178
P577
2013-11-01T00:00:00Z