about
Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoinThe human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structuresAn EST-based approach for identifying genes expressed in the intestine and gills of pre-smolt Atlantic salmon (Salmo salar).preAssemble: a tool for automatic sequencer trace data processing.Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility lociStructural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeatsAnnotated expressed sequence tags (ESTs) from pre-smolt Atlantic salmon (Salmo salar) in a searchable data resource.Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitisSchizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histonesIdentification and characterization of novel mutations in the human gene encoding the catalytic subunit Calpha of protein kinase A (PKA).Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci.Effects of conserved residues and naturally occurring mutations on Mycobacterium tuberculosis RecG helicase activity.DNA base repair--recognition and initiation of catalysis.Role of the C-terminal domain of PCSK9 in degradation of the LDL receptors.Mutations affecting the transmembrane domain of the LDL receptor: impact of charged residues on the membrane insertion.Pathogenic variants in KCTD7 perturb neuronal K+ fluxes and glutamine transport.Removal of acidic residues of the prodomain of PCSK9 increases its activity towards the LDL receptor.Studies on multiple forms of proGRP in serum from small cell lung cancer patients.Schizosaccharomyces pombe encodes a mutated AP endonuclease 1.Investigations on the evolutionary conservation of PCSK9 reveal a functionally important protrusion.Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reticulum.Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms.Expression and purification of NEIL3, a human DNA glycosylase homolog.Mutation S462P in the PCSK9 gene reduces secretion of mutant PCSK9 without affecting the autocatalytic cleavage.Characterization of novel mutations in the catalytic domain of the PCSK9 gene.Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants.Nucleophilic identity substitution reactions. The reaction between water and protonated alcohols.Mutation p.L799R in the LDLR, which affects the transmembrane domain of the LDLR, prevents membrane insertion and causes secretion of the mutant LDLR.Interaction between the ligand-binding domain of the LDL receptor and the C-terminal domain of PCSK9 is required for PCSK9 to remain bound to the LDL receptor during endosomal acidification.Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins.The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity.The vibrational spectrum of camphor from ab initio and density functional theory and parity violation in the C–C*–CO bending modeNucleophilic identity substitution reactions. The reaction between hydrogen fluoride and protonated alkyl fluoridesNucleophilic identity substitution reactions. The reaction between ammonia and protonated aminesPart II. For Part I, see preceding paper (DOI: 10.1039/b302268d).Electronic supplementary information (ESI) available: Cartesian co-ordinates for all specFully Relativistic Coupled Cluster Treatment for Parity-Violating Energy Differences in MoleculesSearch for a Parity-Violating Energy Difference between Enantiomers of a Chiral Iron ComplexComplex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoformCharacterization of the mechanisms by which missense mutations in the lysosomal acid lipase gene disrupt enzymatic activityThe DIRAC code for relativistic molecular calculations
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jon K Laerdahl
@nl
Jon K Laerdahl
@sl
Jon K. Laerdahl
@en
Jon K. Laerdahl
@es
type
label
Jon K Laerdahl
@nl
Jon K Laerdahl
@sl
Jon K. Laerdahl
@en
Jon K. Laerdahl
@es
altLabel
Jon K. Laerdahl
@en
Jon Kristen Lærdahl
@en
prefLabel
Jon K Laerdahl
@nl
Jon K Laerdahl
@sl
Jon K. Laerdahl
@en
Jon K. Laerdahl
@es
P106
P1153
6602156518
P21
P31
P496
0000-0002-0826-9464