about
Selective impairment of platelet activation to collagen in the absence of GATA1A germline mutation in BLOC1S3/reduced pigmentation causes a novel variant of Hermansky-Pudlak syndrome (HPS8)The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expressionIdentification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomainsDifferential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in plateletsDC-SIGN and CLEC-2 mediate human immunodeficiency virus type 1 capture by plateletsGenotyping and phenotyping of platelet function disordersPlatelet lipidomics: modern day perspective on lipid discovery and characterization in plateletsPlatelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling.The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitorsPlatelets: No longer bystanders in liver diseaseA novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and functionTyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in plateletsSerine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinasesEvidence that phospholipase C-gamma2 interacts with SLP-76, Syk, Lyn, LAT and the Fc receptor gamma-chain after stimulation of the collagen receptor glycoprotein VI in human plateletsPlatelet-collagen interaction: is GPVI the central receptor?Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteinsTowards complete analysis of the platelet proteomeAssociation of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signalingInteraction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI50th anniversary of the discovery of ibuprofen: an interview with Dr Stewart AdamsIdentification of the phosphorylation sites of cytosolic phospholipase A2 in agonist-stimulated human platelets and HeLa cellsIdentification and expression of G-proteins in human myometrium: up-regulation of G alpha s in pregnancyThe identification of a selective dopamine D2 partial agonist, D3 antagonist displaying high levels of brain exposureCharacterization of Grb2-binding proteins in human platelets activated by Fc gamma RIIA cross-linkingThe action of the protein kinase C inhibitor, staurosporine, on human platelets. Evidence against a regulatory role for protein kinase C in the formation of inositol trisphosphate by thrombinVPS33B regulates protein sorting into and maturation of α-granule progenitor organelles in mouse megakaryocytesPKCalpha regulates platelet granule secretion and thrombus formation in miceThe tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosisThe Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagenMegakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function.Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet functionSynergy between Ca2+ and protein kinase C is the major factor in determining the level of secretion from human plateletsA collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C gamma2 in platelets independent of the integrin alpha2beta1SLFN14 mutations underlie thrombocytopenia with excessive bleeding and platelet secretion defectsG6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2Renal cells activate the platelet receptor CLEC-2 through podoplaninDocking protein Gab2 positively regulates glycoprotein VI-mediated platelet activation.SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase.Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen.
P50
Q24294468-22CABE15-1FE6-427E-9939-F644CE09C47BQ24300085-5D7DBD75-5FAD-4EDD-B545-CE73DEE5AB26Q24300299-CF84B74F-FECD-402B-BF87-6461F496AB3AQ24313296-B2475CAB-D145-4B25-A5D3-2A1F1C6F30E0Q24534153-FA58B13C-1572-4555-AD60-9FA47CD2D77AQ24673797-3D2BB5DF-DB74-4F2F-959C-9095D3B2DB10Q26860264-C1FBD23F-81E0-4E41-B434-2F9375EFDC40Q26998976-21DE4097-F55D-4D02-8F32-F8C4ED5327BEQ27342857-4A64F551-5255-40BF-AF9D-3E8915F62697Q27657147-263FD45D-E5FE-4FAD-BE78-6E53E2444CEBQ28071893-2F9EAE02-0BB7-4B75-95F1-49D1D44ABB19Q28115628-8B4458A6-02D1-47A5-9AF8-853A1F2B414EQ28137651-F54AF92C-EA0A-49EB-BB34-1B10CA3C800DQ28138060-514E6153-63B4-4C57-A436-5C78796E3885Q28143368-25D43B8E-16AB-41D6-851B-F61EF5D32EEDQ28185377-B458925F-FE29-4FD8-BA0B-E6ABE6D46C64Q28188035-FF7701AB-14DB-4F5A-8E31-0F93F38CD880Q28211303-6B15CC2A-7E39-45D7-BA68-D4F062191FD3Q28214216-34B206B8-E459-4EFF-A4A9-8DB0A56A8015Q28217508-1D84CEB8-B466-4F88-93D5-8C21C9C3FA20Q28253389-E587BCFA-B65B-43B5-80AE-3CB860FFDD3DQ28262222-5B375CDF-A9C8-4C37-BC5D-326737A3A106Q28269703-70DF2EA7-A550-4B46-B32E-02BF93147B13Q28273139-330FDDBD-9E98-457B-A8A0-D4EA1C725F1BQ28283818-F6A52B0B-179B-4985-A128-0D3558C58E4BQ28361275-7713E2DA-E194-4C90-B1E7-4D18D22C1517Q28504778-048A43F2-ADE8-4BFD-A137-74BF03AD76F2Q28505136-1DEBE472-D28B-4CD4-8358-20CF12907060Q28509969-2BE7D856-6654-41AD-878F-0C2C7342C7C5Q28584694-D5D34BF0-9C7F-4A4D-9E2F-6077362250C6Q28587122-25648388-87E0-4C62-AA67-76CC5434CBB2Q28592055-5E384041-8C25-4E5A-B0DD-3A74DD20E4E5Q28609210-C03B0959-F200-4A37-9571-0159FA4DB2EEQ28626656-923FB55C-DE85-44D1-9E07-5E5408F7A46DQ29147411-87DB736F-FF28-4C28-AA9D-F5F14105C859Q29347516-46CEDFEE-611B-4AF7-B490-7585A9133F85Q29347557-2489368A-687E-445C-B44D-69675646A460Q30160118-259401E8-7FAF-4793-B375-F5D1223EE539Q30160823-0E1C366F-ACE4-4E9E-BACC-935817412BF7Q30163810-208CF6D2-0DE9-40A6-ACCB-DC312E850051
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Steve P Watson
@nl
Steve P Watson
@sl
Steve P. Watson
@en
Steve P. Watson
@es
type
label
Steve P Watson
@nl
Steve P Watson
@sl
Steve P. Watson
@en
Steve P. Watson
@es
altLabel
Steve P Watson
@en
prefLabel
Steve P Watson
@nl
Steve P Watson
@sl
Steve P. Watson
@en
Steve P. Watson
@es
P1053
Q-6292-2016
P106
P21
P31
P3829
P496
0000-0002-7846-7423