Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas
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Ovarian serous carcinoma: recent concepts on its origin and carcinogenesisRecent concepts of ovarian carcinogenesis: type I and type IIG-DOC Plus - an integrative bioinformatics platform for precision medicine.A novel KCNQ4 mutation and a private IMMP2L-DOCK4 duplication segregating with nonsyndromic hearing loss in a Brazilian familySingle-nucleotide polymorphisms among microRNA: big effects on cancer.Genome-wide analysis of gynecologic cancer: The Cancer Genome Atlas in ovarian and endometrial cancer.Frequent downregulation of miR-34 family in human ovarian cancers.Update on rare epithelial ovarian cancers: based on the Rare Ovarian Tumors Young Investigator Conference.The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theoryDNA copy numbers profiles in affinity-purified ovarian clear cell carcinomaWhole exome sequence analysis of serous borderline tumors of the ovary.KRAS (but not BRAF) mutations in ovarian serous borderline tumour are associated with recurrent low-grade serous carcinomaOvarian cancer development and metastasis.Chromosome 3 anomalies investigated by genome wide SNP analysis of benign, low malignant potential and low grade ovarian serous tumours.BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas.Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome.Activation of the MEK-S6 pathway in high-grade ovarian cancers.TAGCNA: a method to identify significant consensus events of copy number alterations in cancer.Genome-wide identification of significant aberrations in cancer genome.Distinct DNA methylation profiles in ovarian serous neoplasms and their implications in ovarian carcinogenesis.Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses.Comparative analysis of methods for identifying recurrent copy number alterations in cancer.Molecular characterization of serous ovarian carcinoma using a multigene next generation sequencing cancer panel approach.Somatic mutations, allele loss, and DNA methylation of the Cub and Sushi Multiple Domains 1 (CSMD1) gene reveals association with early age of diagnosis in colorectal cancer patientsmiR-34 - a microRNA replacement therapy is headed to the clinic.Somatic mutations of PPP2R1A in ovarian and uterine carcinomasCancer-associated fibroblasts and their putative role in potentiating the initiation and development of epithelial ovarian cancer.Amplification of the ch19p13.2 NACC1 locus in ovarian high-grade serous carcinomaModeling high-grade serous ovarian carcinogenesis from the fallopian tubeOvarian low-grade and high-grade serous carcinoma: pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problemsGenomic instability and copy-number heterogeneity of chromosome 19q, including the kallikrein locus, in ovarian carcinomas.BRAF mutation is associated with a specific cell type with features suggestive of senescence in ovarian serous borderline (atypical proliferative) tumorsIntratumoral heterogeneity in a minority of ovarian low-grade serous carcinomasHigh level of chromosomal aberration in ovarian cancer genome correlates with poor clinical outcomeG-DOC: a systems medicine platform for personalized oncologyThe new face of ovarian cancer modeling: better prospects for detection and treatment.Mutant BRAF induces DNA strand breaks, activates DNA damage response pathway, and up-regulates glucose transporter-1 in nontransformed epithelial cells.Ovarian Cancer Is an Imported Disease: Fact or Fiction?Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian cancer.Impact of Age and Primary Disease Site on Outcome in Women With Low-Grade Serous Carcinoma of the Ovary or Peritoneum: Results of a Large Single-Institution Registry of a Rare Tumor.
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P2860
Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 21 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Analysis of DNA copy number al ...... rade and high-grade carcinomas
@en
Analysis of DNA copy number al ...... ade and high-grade carcinomas.
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type
label
Analysis of DNA copy number al ...... rade and high-grade carcinomas
@en
Analysis of DNA copy number al ...... ade and high-grade carcinomas.
@nl
prefLabel
Analysis of DNA copy number al ...... rade and high-grade carcinomas
@en
Analysis of DNA copy number al ...... ade and high-grade carcinomas.
@nl
P2093
P2860
P1433
P1476
Analysis of DNA copy number al ...... rade and high-grade carcinomas
@en
P2093
Ie-Ming Shih
Kuan-Ting Kuo
Natini Jinawath
Robert J Kurman
Tian-Li Wang
Tsui-Lien Mao
Yuanjian Feng
P2860
P304
P356
10.1158/0008-5472.CAN-08-3913
P407
P577
2009-04-21T00:00:00Z