Rationale for peptide and DNA based epitope vaccines for Alzheimer's disease immunotherapy.
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The MultiTEP platform-based Alzheimer's disease epitope vaccine activates a broad repertoire of T helper cells in nonhuman primates.DNA prime-protein boost increased the titer, avidity and persistence of anti-Abeta antibodies in wild-type mice.Co-immunization with DNA and protein mixture: a safe and efficacious immunotherapeutic strategy for Alzheimer's disease in PDAPP miceDNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease.Improving Multi-Epitope Long Peptide Vaccine Potency by Using a Strategy that Enhances CD4+ T Help in BALB/c Mice.Immunogenicity, efficacy, safety, and mechanism of action of epitope vaccine (Lu AF20513) for Alzheimer's disease: prelude to a clinical trialEpitope-based DNA vaccine for Alzheimer's disease: translational study in macaques.Refinement of a DNA based Alzheimer's disease epitope vaccine in rabbits.Can Alzheimer disease be prevented by amyloid-beta immunotherapy?Plant-based vaccines for Alzheimer's disease: an overview.Comparison of Efficacy of Preventive and Therapeutic Vaccines Targeting the N Terminus of β-Amyloid in an Animal Model of Alzheimer's Disease.MultiTEP platform-based DNA vaccines for alpha-synucleinopathies: preclinical evaluation of immunogenicity and therapeutic potency.
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Rationale for peptide and DNA based epitope vaccines for Alzheimer's disease immunotherapy.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Rationale for peptide and DNA ...... eimer's disease immunotherapy.
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Rationale for peptide and DNA ...... eimer's disease immunotherapy.
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type
label
Rationale for peptide and DNA ...... eimer's disease immunotherapy.
@en
Rationale for peptide and DNA ...... eimer's disease immunotherapy.
@nl
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Rationale for peptide and DNA ...... eimer's disease immunotherapy.
@en
Rationale for peptide and DNA ...... eimer's disease immunotherapy.
@nl
P2860
P1476
Rationale for peptide and DNA ...... eimer's disease immunotherapy.
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P2093
Anahit Ghochikyan
P2860
P304
P356
10.2174/187152709787847298
P577
2009-04-01T00:00:00Z