Low-dose dasatinib rescues cardiac function in Noonan syndrome. - Wikidata - thesis-toulmin - TriplyDB

Low-dose dasatinib rescues cardiac function in Noonan syndrome.

Low-dose dasatinib rescues cardiac function in Noonan syndrome.

http://www.wikidata.org/entity/Q37469169

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Targeting cellular senescence prevents age-related bone loss in mice.Recent Advances in Understanding and Managing Cardiomyopathy.

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Low-dose dasatinib rescues cardiac function in Noonan syndrome.

http://www.wikidata.org/entity/Q37469169

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 08 December 2016

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

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name

Low-dose dasatinib rescues cardiac function in Noonan syndrome.

@en

Low-dose dasatinib rescues cardiac function in Noonan syndrome.

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type

label

Low-dose dasatinib rescues cardiac function in Noonan syndrome.

@en

Low-dose dasatinib rescues cardiac function in Noonan syndrome.

@nl

prefLabel

Low-dose dasatinib rescues cardiac function in Noonan syndrome.

@en

Low-dose dasatinib rescues cardiac function in Noonan syndrome.

@nl

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JCI.INSIGHT.90220

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Low-dose dasatinib rescues cardiac function in Noonan syndrome.

@en

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Andrea T Kwaczala

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Anton M Bennett

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Barbara E Ehrlich

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Frank J Giordano

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Ivana Y Kuo

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Jae-Sung Yi

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Stuart G Campbell

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Yan Huang

http://www.w3.org/2001/XMLSchema#string

P2860

Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2

Dissecting the interaction of SHP-2 with PZR, an immunoglobulin family protein containing immunoreceptor tyrosine-based inhibitory motifs

Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor

Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras

Molecular Basis of Gain-of-Function LEOPARD Syndrome-Associated SHP2 Mutations

Crystal structure of the tyrosine phosphatase SHP-2

Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation

Gain-of-function/Noonan syndrome SHP-2/Ptpn11 mutants enhance calcium oscillations and impair NFAT signaling

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e90220

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scholarly article

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10.1172/JCI.INSIGHT.90220

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2016-12-08T00:00:00Z

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