The contribution of epistasis to the architecture of fitness in an RNA virus.
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Long intervals of stasis punctuated by bursts of positive selection in the seasonal evolution of influenza A virusDistribution of Fitness and Virulence Effects Caused by Single-Nucleotide Substitutions in Tobacco Etch VirusMutational fitness effects in RNA and single-stranded DNA viruses: common patterns revealed by site-directed mutagenesis studiesThe causes of epistasisHepatitis C virus adaptation to T-cell immune pressureOrigin and proliferation of multiple-drug resistance in bacterial pathogensMechanisms of genetic robustness in RNA virusesCoordinated evolution of the hepatitis C virusSelection for robustness in mutagenized RNA virusesPervasive sign epistasis between conjugative plasmids and drug-resistance chromosomal mutationsPrevalence of epistasis in the evolution of influenza A surface proteinsFitness ranking of individual mutants drives patterns of epistatic interactions in HIV-1Evolutionary ecology of virus emergence.The conversion of variance and the evolutionary potential of restricted recombination.Fisher's geometric model of adaptation meets the functional synthesis: data on pairwise epistasis for fitness yields insights into the shape and size of phenotype spaceQuantifying organismal complexity using a population genetic approachConstraints to genetic exchange support gene coadaptation in a tripartite RNA virus.Understanding the evolutionary fate of finite populations: the dynamics of mutational effects.Analysis of epistatic interactions and fitness landscapes using a new geometric approachLethal mutants and truncated selection together solve a paradox of the origin of lifeA network model for the correlation between epistasis and genomic complexity.Predicting the evolution of sex on complex fitness landscapes.Drug interactions and the evolution of antibiotic resistance.Exploring the fitness landscape of an RNA virus by using a universal barcode microarrayFitness epistasis and constraints on adaptation in a human immunodeficiency virus type 1 protein regionExtensive recombination-induced disruption of genetic interactions is highly deleterious but can be partially reversed by small numbers of secondary recombination eventsEpistasis between beneficial mutations and the phenotype-to-fitness Map for a ssDNA virus.Quasispecies spatial models for RNA viruses with different replication modes and infection strategies.Identification of genetically modified Maraba virus as an oncolytic rhabdovirus.Evolution of hepatitis delta virus RNA genome following long-term replication in cell culture.Why do RNA viruses recombine?The population genetics of X-autosome synthetic lethals and steriles.The consistency of beneficial fitness effects of mutations across diverse genetic backgrounds.The effect of bacterial recombination on adaptation on fitness landscapes with limited peak accessibilityEvolution at increased error rate leads to the coexistence of multiple adaptive pathways in an RNA virus.Epistasis for fitness-related quantitative traits in Arabidopsis thaliana grown in the field and in the greenhouse.Analysis of the evolution and structure of a complex intrahost viral population in chronic hepatitis C virus mapped by ultradeep pyrosequencing.A systematic survey of an intragenic epistatic landscape.Properties of selected mutations and genotypic landscapes under Fisher's geometric model.Epistasis correlates to genomic complexity.
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The contribution of epistasis to the architecture of fitness in an RNA virus.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 October 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The contribution of epistasis to the architecture of fitness in an RNA virus.
@en
The contribution of epistasis to the architecture of fitness in an RNA virus.
@nl
type
label
The contribution of epistasis to the architecture of fitness in an RNA virus.
@en
The contribution of epistasis to the architecture of fitness in an RNA virus.
@nl
prefLabel
The contribution of epistasis to the architecture of fitness in an RNA virus.
@en
The contribution of epistasis to the architecture of fitness in an RNA virus.
@nl
P2860
P356
P1476
The contribution of epistasis to the architecture of fitness in an RNA virus.
@en
P2093
Rafael Sanjuán
P2860
P304
15376-15379
P356
10.1073/PNAS.0404125101
P407
P577
2004-10-18T00:00:00Z