Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing. - Wikidata - thesis-toulmin - TriplyDB

Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing.

Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing.

http://www.wikidata.org/entity/Q37593646

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The quest for mammalian Polycomb response elements: are we there yet?Maintenance of Tissue Pluripotency by Epigenetic Factors Acting at Multiple Levels Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins.Trithorax maintains the functional heterogeneity of neural stem cells through the transcription factor buttonhead.Histone H3 globular domain acetylation identifies a new class of enhancers.Polycomb-mediated gene silencing in Arabidopsis thaliana.Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation Sex comb on midleg (Scm) is a functional link between PcG-repressive complexes in Drosophila Genome-wide activities of Polycomb complexes control pervasive transcription.Phenotypic Plasticity through Transcriptional Regulation of the Evolutionary Hotspot Gene tan in Drosophila melanogaster.dBRWD3 Regulates Tissue Overgrowth and Ectopic Gene Expression Caused by Polycomb Group Mutations.LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection.CBP binding outside of promoters and enhancers in Drosophila melanogaster.Polycomb inhibits histone acetylation by CBP by binding directly to its catalytic domain.Contribution of Neuroepigenetics to Huntington's Disease.Polycomb group proteins--epigenetic repressors with emerging roles in melanocytes and melanoma.Diabetes mellitus--advances and challenges in human β-cell proliferation.Eukaryotic enhancers: common features, regulation, and participation in diseases.Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors.Slow Chromatin Dynamics Allow Polycomb Target Genes to Filter Fluctuations in Transcription Factor Activity.Developmental transcriptional regulation by SUMOylation, an evolving field.Striatal H3K27 Acetylation Linked to Glutamatergic Gene Dysregulation in Human Heroin Abusers Holds Promise as Therapeutic Target.RNF40 regulates gene expression in an epigenetic context-dependent manner.The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.Polycomb and Trithorax Group Genes in Drosophila.Trithorax dependent changes in chromatin landscape at enhancer and promoter regions drive female puberty.ATX3, ATX4, and ATX5 Encode Putative H3K4 Methyltransferases and Are Critical for Plant Development.[Epigenetic regulations and cerebral plasticity: towards new therapeutic options in neurodegenerative diseases?]Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization

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Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing.

http://www.wikidata.org/entity/Q37593646

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on March 2014

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Trithorax monomethylates histo ...... antagonize Polycomb silencing.

@en

Trithorax monomethylates histo ...... antagonize Polycomb silencing.

@nl

type

label

Trithorax monomethylates histo ...... antagonize Polycomb silencing.

@en

Trithorax monomethylates histo ...... antagonize Polycomb silencing.

@nl

prefLabel

Trithorax monomethylates histo ...... antagonize Polycomb silencing.

@en

Trithorax monomethylates histo ...... antagonize Polycomb silencing.

@nl

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Trithorax monomethylates histo ...... antagonize Polycomb silencing

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Alina R Saiakhova

http://www.w3.org/2001/XMLSchema#string

Benny Howard

http://www.w3.org/2001/XMLSchema#string

Kelsey E Monteith

http://www.w3.org/2001/XMLSchema#string

Michael S Cosgrove

http://www.w3.org/2001/XMLSchema#string

Peter C Scacheri

http://www.w3.org/2001/XMLSchema#string

Peter J Harte

http://www.w3.org/2001/XMLSchema#string

Rakhee Banerjee

http://www.w3.org/2001/XMLSchema#string

P2860

Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression

Leu628 of the KIX domain of CBP is a key residue for the interaction with the MLL transactivation domain

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression

On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

In vitro and in vivo analyses of a Phe/Tyr switch controlling product specificity of histone lysine methyltransferases

Combinatorial patterns of histone acetylations and methylations in the human genome

Mapping the interactions of the p53 transactivation domain with the KIX domain of CBP

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1129-1139

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scholarly article

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10.1242/DEV.102392

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5

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141

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2014-03-01T00:00:00Z

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24550119

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3929413

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