Beta-cell deterioration during diabetes: what's in the gun?
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The mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseasesUCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in β-cells: evidence of interplay between the ubiquitin/proteasome system and autophagyA combined analysis of 48 type 2 diabetes genetic risk variants shows no discriminative value to predict time to first prescription of a glucose lowering drug in Danish patients with screen detected type 2 diabetesPancreatic β-cell dysfunction in polycystic ovary syndrome: role of hyperglycemia-induced nuclear factor-κB activation and systemic inflammation.Gestational diabetes mellitus: a positive predictor of type 2 diabetes?Protection of pancreatic beta-cells from various stress conditions is mediated by DJ-1Clinical and genetic determinants of progression of type 2 diabetes: a DIRECT studyIn vivo pancreatic β-cell-specific expression of antiaging gene Klotho: a novel approach for preserving β-cells in type 2 diabetesAdiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regenerationPPAR-γ activation restores pancreatic islet SERCA2 levels and prevents β-cell dysfunction under conditions of hyperglycemic and cytokine stress.Dual Opposing Roles of Metallothionein Overexpression in C57BL/6J Mouse Pancreatic β-Cells.Bone marrow-derived mesenchymal stem cells ameliorate chronic high glucose-induced β-cell injury through modulation of autophagySystematic investigation into the role of intermittent high glucose in pancreatic beta-cells.Antioxidants Complement the Requirement for Protein Chaperone Function to Maintain β-Cell Function and Glucose Homeostasis.Combined effect of hydrogen sulphide donor and losartan in experimental diabetic nephropathy in ratsThe role of mitochondria in the pathogenesis of type 2 diabetesCompensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics.Low Level Pro-inflammatory Cytokines Decrease Connexin36 Gap Junction Coupling in Mouse and Human Islets through Nitric Oxide-mediated Protein Kinase Cδ.Update on the protective molecular pathways improving pancreatic beta-cell dysfunctionThe role of peroxisome proliferator-activated receptor γ in pancreatic β cell function and survival: therapeutic implications for the treatment of type 2 diabetes mellitus.Glucose-stimulated oxidative stress in mononuclear cells is related to pancreatic β-cell dysfunction in polycystic ovary syndrome.New insights into the role of connexins in pancreatic islet function and diabetes.Oxidative stress and the ageing endocrine system.Induction of receptor for advanced glycation end products by insufficient leptin action triggers pancreatic β-cell failure in type 2 diabetes.DPP-4 (CD26) inhibitor sitagliptin exerts anti-inflammatory effects on rat insulinoma (RINm) cells via suppressing NF-κB activation.Pyruvate kinase, muscle isoform 2 promotes proliferation and insulin secretion of pancreatic β-cells via activating Wnt/CTNNB1 signaling.The effect of different volumes of high-intensity interval training on proinsulin in participants with the metabolic syndrome: a randomised trial.Hydrogen sulphide protects mouse pancreatic β-cells from cell death induced by oxidative stress, but not by endoplasmic reticulum stress.Endurance training stimulates growth and survival pathways and the redox balance in rat pancreatic islets.Melatonin ameliorates low-grade inflammation and oxidative stress in young Zucker diabetic fatty rats.Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity.Melatonin improves glucose homeostasis in young Zucker diabetic fatty rats.
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P2860
Beta-cell deterioration during diabetes: what's in the gun?
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 11 September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Beta-cell deterioration during diabetes: what's in the gun?
@en
Beta-cell deterioration during diabetes: what's in the gun?
@nl
type
label
Beta-cell deterioration during diabetes: what's in the gun?
@en
Beta-cell deterioration during diabetes: what's in the gun?
@nl
prefLabel
Beta-cell deterioration during diabetes: what's in the gun?
@en
Beta-cell deterioration during diabetes: what's in the gun?
@nl
P2860
P1476
Beta-cell deterioration during diabetes: what's in the gun?
@en
P2093
R Paul Robertson
P2860
P304
P356
10.1016/J.TEM.2009.05.004
P577
2009-09-11T00:00:00Z