Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.

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http://www.wikidata.org/entity/Q37619695
BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells.Metformin and cancer: Quo vadis et cui bono?Individual-specific variation in the respiratory activities of HMECs and their bioenergetic response to IGF1 and TNFα.Metformin inhibits RANKL and sensitizes cancer stem cells to denosumab.Metformin targets histone acetylation in cancer-prone epithelial cells.Branched-chain amino acid metabolism in cancer.Metformin Potentiates the Benefits of Dietary Restraint: A Metabolomic Study.Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism.DNA Damage, Repair, and Cancer Metabolism.Fatty acid synthase (FASN) as a therapeutic target in breast cancer.Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
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Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.

Item
http://www.wikidata.org/entity/Q37619695
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 31 May 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Germline BRCA1 mutation reprog ...... strategies in BRCA1 carriers.
@en
Germline BRCA1 mutation reprog ...... strategies in BRCA1 carriers.
@nl
type
label
Germline BRCA1 mutation reprog ...... strategies in BRCA1 carriers.
@en
Germline BRCA1 mutation reprog ...... strategies in BRCA1 carriers.
@nl
prefLabel
Germline BRCA1 mutation reprog ...... strategies in BRCA1 carriers.
@en
Germline BRCA1 mutation reprog ...... strategies in BRCA1 carriers.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Germline BRCA1 mutation reprog ...... " strategies in BRCA1 carriers
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932