IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking
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Cytokines and cytokine networks target neurons to modulate long-term potentiation.Lentivirus-mediated interleukin-1β (IL-1β) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in mice.Visceral Inflammation and Immune Activation Stress the Brain.Retrograde interferon-gamma signaling induces major histocompatibility class I expression in human-induced pluripotent stem cell-derived neurons.TNFα and IL-1β but not IL-18 Suppresses Hippocampal Long-Term Potentiation Directly at the Synapse.Involvement of Akt/CREB signaling pathways in the protective effect of EPA against interleukin-1β-induced cytotoxicity and BDNF down-regulation in cultured rat hippocampal neurons
P2860
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 02 February 2017
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking
@en
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking.
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type
label
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking
@en
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking.
@nl
prefLabel
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking
@en
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking.
@nl
P2860
P1476
IL-1β impairs retrograde flow of BDNF signaling by attenuating endosome trafficking
@en
P2093
Anthony J Carlos
Carl W Cotman
P2860
P2888
P356
10.1186/S12974-017-0803-Z
P577
2017-02-02T00:00:00Z
P6179
1083523802