A role for XLF in DNA repair and recombination in human somatic cells. - Wikidata - thesis-toulmin - TriplyDB

A role for XLF in DNA repair and recombination in human somatic cells.

A role for XLF in DNA repair and recombination in human somatic cells.

http://www.wikidata.org/entity/Q37628142

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XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB Repair Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV Stimulation XLF-mediated NHEJ activity in hepatocellular carcinoma therapy resistance.Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM.SFPQ•NONO and XLF function separately and together to promote DNA double-strand break repair via canonical nonhomologous end joining.Deficiency of XLF and PAXX prevents DNA double-strand break repair by non-homologous end joining in lymphocytes.FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response.

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A role for XLF in DNA repair and recombination in human somatic cells.

http://www.wikidata.org/entity/Q37628142

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 21 January 2014

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

A role for XLF in DNA repair and recombination in human somatic cells.

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A role for XLF in DNA repair and recombination in human somatic cells.

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type

label

A role for XLF in DNA repair and recombination in human somatic cells.

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A role for XLF in DNA repair and recombination in human somatic cells.

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prefLabel

A role for XLF in DNA repair and recombination in human somatic cells.

@en

A role for XLF in DNA repair and recombination in human somatic cells.

@nl

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J.DNAREP.2013.12.006

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A role for XLF in DNA repair and recombination in human somatic cells.

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Eric A Hendrickson

http://www.w3.org/2001/XMLSchema#string

Eu Han Lee

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Farjana Jahan Fattah

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Junghun Kweon

http://www.w3.org/2001/XMLSchema#string

Natalie Lichter

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Natalie Weisensel

http://www.w3.org/2001/XMLSchema#string

Yinan Kan

http://www.w3.org/2001/XMLSchema#string

Yongbao Wang

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P2860

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

Nonhomologous end joining and V(D)J recombination require an additional factor

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks

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39-53

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scholarly article

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10.1016/J.DNAREP.2013.12.006

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15

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2014-01-21T00:00:00Z

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3948327

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