K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5. - Wikidata - thesis-toulmin - TriplyDB

K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.

K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.

http://www.wikidata.org/entity/Q37686404

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Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential Export of sphingosine-1-phosphate and cancer progression Cellular and molecular regulation of innate inflammatory responses Innate immune interactions within the central nervous system modulate pathogenesis of viral infections Lipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic Targets Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching.Systems immunology reveals markers of susceptibility to West Nile virus infection.Expression of neuronal CXCL10 induced by rabies virus infection initiates infiltration of inflammatory cells, production of chemokines and cytokines, and enhancement of blood-brain barrier permeability.Sphingolipid metabolites in inflammatory disease.RelB/p50 complexes regulate cytokine-induced YKL-40 expression CYLD-mediated signaling and diseases.A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties.NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets.Intracranial Injection of Dengue Virus Induces Interferon Stimulated Genes and CD8+ T Cell Infiltration by Sphingosine Kinase 1 Independent Pathways Dengue Virus-Induced Inflammation of the Endothelium and the Potential Roles of Sphingosine Kinase-1 and MicroRNAs.Sphingosine-1-phosphate inhibits IL-1-induced expression of C-C motif ligand 5 via c-Fos-dependent suppression of IFN-β amplification loop.Transient receptor potential channel 1 maintains adherens junction plasticity by suppressing sphingosine kinase 1 expression to induce endothelial hyperpermeability.Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8+ T-cell axis ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex Targeting Imbalance between IL-1β and IL-1 Receptor Antagonist Ameliorates Delayed Epithelium Wound Healing in Diabetic Mouse Corneas HIV-1 Tat Recruits HDM2 E3 Ligase To Target IRF-1 for Ubiquitination and Proteasomal Degradation.Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants.K63-linked polyubiquitination of IRF1: an essential step in the IL-1 signaling cascade.Resveratrol and its oligomers: modulation of sphingolipid metabolism and signaling in disease.Beyond Immune Cell Migration: The Emerging Role of the Sphingosine-1-phosphate Receptor S1PR4 as a Modulator of Innate Immune Cell Activation.S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1β or Lipocalin-2.Elevated chronic inflammatory factors and myeloid-derived suppressor cells indicate poor prognosis in advanced melanoma patients.Investigation of sphingosine kinase 1 in interferon responses during dengue virus infection.Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis.DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues.A novel function of cIAP1 as a mediator of CHIP-driven eIF4E regulation.Role of Interferon Regulatory Factor 1 in Governing Treg Depletion, Th1 Polarization, Inflammasome Activation and Antitumor Efficacy of Cyclophosphamide.ORMDL proteins regulate ceramide levels during sterile inflammation.Sphingosine-1-phosphate transporters as targets for cancer therapy.S1P promotes breast cancer progression by angiogenesis and lymphangiogenesis The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer.Ehrlichia chaffeensis TRP32 Nucleomodulin Function and Localization Is Regulated by NEDD4L-Mediated Ubiquitination.Sphingolipids role in the regulation of inflammatory response: From leukocyte biology to bacterial infection.Src Family Kinases Regulate Interferon Regulatory Factor 1 K63 Ubiquitination following Activation by TLR7/8 Vaccine Adjuvant in Human Monocytes and B Cells.

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K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.

http://www.wikidata.org/entity/Q37686404

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 26 January 2014

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

K63-linked polyubiquitination ...... of chemokines CXCL10 and CCL5.

@en

K63-linked polyubiquitination ...... of chemokines CXCL10 and CCL5.

@nl

type

label

K63-linked polyubiquitination ...... of chemokines CXCL10 and CCL5.

@en

K63-linked polyubiquitination ...... of chemokines CXCL10 and CCL5.

@nl

prefLabel

K63-linked polyubiquitination ...... of chemokines CXCL10 and CCL5.

@en

K63-linked polyubiquitination ...... of chemokines CXCL10 and CCL5.

@nl

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Nature Immunology

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K63-linked polyubiquitination ...... of chemokines CXCL10 and CCL5.

@en

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Akimitsu Yamada

http://www.w3.org/2001/XMLSchema#string

Cheng Luo

http://www.w3.org/2001/XMLSchema#string

Clement Oyeniran

http://www.w3.org/2001/XMLSchema#string

Jeremy C Allegood

http://www.w3.org/2001/XMLSchema#string

Jessie W Yester

http://www.w3.org/2001/XMLSchema#string

Kuzhuvelil B Harikumar

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Megan M Price

http://www.w3.org/2001/XMLSchema#string

Michael J Surace

http://www.w3.org/2001/XMLSchema#string

Nitai C Hait

http://www.w3.org/2001/XMLSchema#string

Reetika Bhardwaj

http://www.w3.org/2001/XMLSchema#string

P2860

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

Docking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIP

Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

Induction of IFN-β and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7

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LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

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10.1038/NI.2810

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3

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Michael S. Diamond

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2014-01-26T00:00:00Z

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