The dual kinase complex FAK-Src as a promising therapeutic target in cancer - Wikidata - thesis-toulmin - TriplyDB

The dual kinase complex FAK-Src as a promising therapeutic target in cancer

The dual kinase complex FAK-Src as a promising therapeutic target in cancer

http://www.wikidata.org/entity/Q37771259

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Digitoxin and its analogs as novel cancer therapeutics New insights into FAK function and regulation during spermatogenesis Resistance and escape from antiangiogenesis therapy: clinical implications and future strategies Role of non-receptor protein tyrosine kinases in spermatid transport during spermatogenesis FAK in cancer: mechanistic findings and clinical applications The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation.Impacts of environmental toxicants on male reproductive dysfunction Inactivation of Src-to-ezrin pathway: a possible mechanism in the ouabain-mediated inhibition of A549 cell migration The blood-testis barrier and its implications for male contraception Palladin is a regulator of actin filament bundles at the ectoplasmic specialization in adult rat testes Simultaneous deactivation of FAK and Src improves the pathology of hypertrophic scar Tissue stiffness dictates development, homeostasis, and disease progression.Significance of talin in cancer progression and metastasis.Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells Subcellular localization of total and activated Src kinase in African American and Caucasian breast cancer Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells PAUF promotes adhesiveness of pancreatic cancer cells by modulating focal adhesion kinase.1'-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway.The β1-integrin-p-FAK-p130Cas-DOCK180-RhoA-vinculin is a novel regulatory protein complex at the apical ectoplasmic specialization in adult rat testes.Ultrasmall integrin-targeted silica nanoparticles modulate signaling events and cellular processes in a concentration-dependent manner.Endothelial FAK as a therapeutic target in disease.Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer.LAMC2 enhances the metastatic potential of lung adenocarcinoma.Early Candidate Biomarkers of Non-Small Cell Lung Cancer Are Screened and Identified in Premalignant Lung Lesions.Extracellular component hyaluronic acid and its receptor Hmmr are required for epicardial EMT during heart regeneration.Elevated Src expression associated with hepatocellular carcinoma metastasis in northern Chinese patients Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers.Focal adhesion kinase autophosphorylation inhibition decreases colon cancer cell growth and enhances the efficacy of chemotherapy.DEspR roles in tumor vasculo-angiogenesis, invasiveness, CSC-survival and anoikis resistance: a 'common receptor coordinator' paradigm.Aurora kinase A revives dormant laryngeal squamous cell carcinoma cells via FAK/PI3K/Akt pathway activation.Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling.Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer.Ambivalent role of pFAK-Y397 in serous ovarian cancer--a study of the OVCAD consortium.Occurrence and significance of epithelial-mesenchymal transition in breast cancer.Targeting focal adhesion kinase in fibrotic diseases.Targeting FAK in human cancer: from finding to first clinical trials.Angiogenesis in cancer: Anti-VEGF escape mechanisms Cell-cell and cell-matrix adhesion in survival and metastasis: Stat3 versus Akt.Multifaceted ability of naturally occurring polyphenols against metastatic cancer.Thyroid Hormone Controls Breast Cancer Cell Movement via Integrin αV/β3/SRC/FAK/PI3-Kinases.

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The dual kinase complex FAK-Src as a promising therapeutic target in cancer

http://www.wikidata.org/entity/Q37771259

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 24 June 2010

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The dual kinase complex FAK-Src as a promising therapeutic target in cancer

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The dual kinase complex FAK-Src as a promising therapeutic target in cancer.

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type

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The dual kinase complex FAK-Src as a promising therapeutic target in cancer

@en

The dual kinase complex FAK-Src as a promising therapeutic target in cancer.

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prefLabel

The dual kinase complex FAK-Src as a promising therapeutic target in cancer

@en

The dual kinase complex FAK-Src as a promising therapeutic target in cancer.

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OncoTargets and Therapy

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The dual kinase complex FAK-Src as a promising therapeutic target in cancer

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Enrique Grande

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Joan Manuel Gasent

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Victoria Bolós

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P2860

Epidermal growth factor directs sex-specific steroid signaling through Src activation

Integrin-regulated FAK-Src signaling in normal and cancer cells

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation

Src family kinases in tumor progression and metastasis

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

A SARCOMA OF THE FOWL TRANSMISSIBLE BY AN AGENT SEPARABLE FROM THE TUMOR CELLS

Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.

Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271

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83-97

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scholarly article

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10.2147/OTT.S6909

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3

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Sara López-Tarruella

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2010-06-24T00:00:00Z

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20616959

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2895777

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