Translational control gone awry: a new mechanism of tumorigenesis and novel targets of cancer treatments.
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The translation initiation factor eIF3i up-regulates vascular endothelial growth factor A, accelerates cell proliferation, and promotes angiogenesis in embryonic development and tumorigenesis.Identification of phenotype-relevant differentially expressed genes in breast cancer demonstrates enhanced quantile discretization protocol's utility in multi-platform microarray data integration.Association of positively selected eIF3a polymorphisms with toxicity of platinum-based chemotherapy in NSCLC patientsRole of eIF3a in regulating cisplatin sensitivity and in translational control of nucleotide excision repair of nasopharyngeal carcinoma.Translational regulation of RPA2 via internal ribosomal entry site and by eIF3aOverexpression of eIF3a in Squamous Cell Carcinoma of the Oral Cavity and Its Putative Relation to Chemotherapy Response.Post-transcriptional regulation in cancer progression : Microenvironmental control of alternative splicing and translation.eIF3a improve cisplatin sensitivity in ovarian cancer by regulating XPC and p27Kip1 translation.Spectrin domain of eukaryotic initiation factor 3a is the docking site for formation of the a:b:i:g subcomplex.Eukaryotic Translation Initiation Factor 3a (eIF3a) Promotes Cell Proliferation and Motility in Pancreatic Cancer.MicroRNA-138 acts as a tumor suppressor in non small cell lung cancer via targeting YAP1EIF3i promotes colon oncogenesis by regulating COX-2 protein synthesis and β-catenin activation.Deletion of eIF2β lysine stretches creates a dominant negative that affects the translation and proliferation in human cell line: A tool for arresting the cell growth.Pharmacogenomics of platinum-based chemotherapy sensitivity in NSCLC: toward precision medicine.Synthesis, pharmacophores, and mechanism study of pyridin-2(1H)-one derivatives as regulators of translation initiation factor 3A.Impact of a Eukaryotic Translation Initiation Factor 3a Polymorphism on Susceptibility to Gastric Cancer.eIF3 Regulation of Protein Synthesis, Tumorigenesis, and Therapeutic Response.eIF2β, a subunit of translation-initiation factor EIF2, is a potential therapeutic target for non-small cell lung cancer.The Biological Roles of Translation Initiation Factor 3b
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Translational control gone awry: a new mechanism of tumorigenesis and novel targets of cancer treatments.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Translational control gone awr ...... targets of cancer treatments.
@en
Translational control gone awr ...... targets of cancer treatments.
@nl
type
label
Translational control gone awr ...... targets of cancer treatments.
@en
Translational control gone awr ...... targets of cancer treatments.
@nl
prefLabel
Translational control gone awr ...... targets of cancer treatments.
@en
Translational control gone awr ...... targets of cancer treatments.
@nl
P2093
P2860
P356
P1433
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Translational control gone awr ...... targets of cancer treatments.
@en
P2093
Jian-Ting Zhang
Zizheng Dong
P2860
P356
10.1042/BSR20100077
P577
2011-02-01T00:00:00Z