about
Wnt Signaling in Cancer Stem Cell BiologyCancer heterogeneity--a multifaceted viewColorectal cancer heterogeneity and targeted therapy: a case for molecular disease subtypesModeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumorsBidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneityThe effect of environmental chemicals on the tumor microenvironmentAssessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge aheadWnt activity defines colon cancer stem cells and is regulated by the microenvironmentCD44 expression in intestinal epithelium and colorectal cancer is independent of p53 statusFusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis.The consensus molecular subtypes of colorectal cancerBcl-2 is a critical mediator of intestinal transformationCancer stem cells--old concepts, new insights.CFTR is a tumor suppressor gene in murine and human intestinal cancerA multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype.Reconciliation of classification systems defining molecular subtypes of colorectal cancer: interrelationships and clinical implications.Targeting Wnt signaling in colon cancer stem cells.Microenvironmental regulation of stem cells in intestinal homeostasis and cancer.The developing cancer stem-cell model: clinical challenges and opportunities.Dissecting cancer heterogeneity--an unsupervised classification approach.Stem cell dynamics in homeostasis and cancer of the intestine.Serrated neoplasia-role in colorectal carcinogenesis and clinical implications.Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer.Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry.TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype.One renegade cancer stem cell?Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.ER-Stress-Induced Differentiation Sensitizes Colon Cancer Stem Cells to Chemotherapy.Stem cell competition: how speeding mutants beat the rest.Polycomb complex PRC1 as gatekeeper of intestinal stem cell identityTurning off the BCL-2 switch to prevent intestinal tumorigenesis.Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients.Intestinal label-retaining cells are secretory precursors expressing Lgr5.Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models.Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas.Defining stem cell dynamics in models of intestinal tumor initiation.Exploring cancer stem cell niche directed tumor growth.The Use of Targeted Therapies for Precision Medicine in Oncology.
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description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Louis Vermeulen
@ast
Louis Vermeulen
@en
Louis Vermeulen
@es
Louis Vermeulen
@nl
Louis Vermeulen
@sl
type
label
Louis Vermeulen
@ast
Louis Vermeulen
@en
Louis Vermeulen
@es
Louis Vermeulen
@nl
Louis Vermeulen
@sl
prefLabel
Louis Vermeulen
@ast
Louis Vermeulen
@en
Louis Vermeulen
@es
Louis Vermeulen
@nl
Louis Vermeulen
@sl
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P21
P2798
P31
P496
0000-0002-6066-789X