miRNA processing and human cancer: DICER1 cuts the mustard.
about
Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repressionLin28 sustains early renal progenitors and induces Wilms tumorSomatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumoursAltered expression of the miRNA processing endoribonuclease Dicer has prognostic significance in human cancers.Dicer promotes transcription termination at sites of replication stress to maintain genome stabilityUnique haploinsufficient role of the microRNA-processing molecule Dicer1 in a murine colitis-associated tumorigenesis model.Germ-line and somatic DICER1 mutations in pineoblastoma.3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.Low DICER1 expression is associated with poor clinical outcome in adrenocortical carcinoma.Major clinical research advances in gynecologic cancer in 2012.Metformin-mediated increase in DICER1 regulates microRNA expression and cellular senescenceSertoli - Leydig cell tumor with retiform areas and overgrowth of rhabdomyosarcomatous elements: case report and literature review.DICER1 hotspot mutations in non-epithelial gonadal tumours.DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastomaRole of Dicer as a prognostic predictor for survival in cancer patients: a systematic review with a meta-analysis.Dicer1 dysfunction promotes stemness and aggression in endometrial carcinoma.Recurrent DICER1 hotspot mutations in endometrial tumours and their impact on microRNA biogenesis.Differential expression of basal microRNAs' patterns in human dental pulp stem cells.Integrated analysis of miRNA and mRNA profiles enables target acquisition in human cancers.High-sensitivity sequencing reveals multi-organ somatic mosaicism causing DICER1 syndrome.MicroRNA Expression: Protein Participants in MicroRNA Regulation.Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage.Reduced DICER1 Expression Bestows Rheumatoid Arthritis Synoviocytes Proinflammatory Properties and Resistance to Apoptotic Stimuli.Non-Coding RNAs and Endometrial Cancer.Dicer affects cisplatin‑mediated apoptosis in epithelial ovarian cancer cells
P2860
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P2860
miRNA processing and human cancer: DICER1 cuts the mustard.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
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2011年學術文章
@zh-hant
name
miRNA processing and human cancer: DICER1 cuts the mustard.
@en
miRNA processing and human cancer: DICER1 cuts the mustard.
@nl
type
label
miRNA processing and human cancer: DICER1 cuts the mustard.
@en
miRNA processing and human cancer: DICER1 cuts the mustard.
@nl
prefLabel
miRNA processing and human cancer: DICER1 cuts the mustard.
@en
miRNA processing and human cancer: DICER1 cuts the mustard.
@nl
P2860
P1476
miRNA processing and human cancer: DICER1 cuts the mustard.
@en
P2093
Amin Bahubeshi
Marc Tischkowitz
P2860
P304
P356
10.1126/SCITRANSLMED.3002493
P407
P577
2011-11-01T00:00:00Z