Illuminating the functional and structural repertoire of human TBC/RABGAPs.
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TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagyLoss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humansMultiple Roles of the Small GTPase Rab7Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)Rab GTPase regulation of membrane identityIdentifying novel spatiotemporal regulators of innate immunityRegulation of small GTPases by GEFs, GAPs, and GDIsRegulators of autophagosome formation in Drosophila musclesCatalytic mechanism of a mammalian Rab{middle dot}RabGAP complex in atomic detailTBCK influences cell proliferation, cell size and mTOR signaling pathwayA paired RNAi and RabGAP overexpression screen identifies Rab11 as a regulator of β-amyloid production.A central role for vesicle trafficking in epithelial neoplasia: intracellular highways to carcinogenesis.Rab1 in cell signaling, cancer and other diseasesEvolution of Tre-2/Bub2/Cdc16 (TBC) Rab GTPase-activating proteinsThe genetic basis of DOORS syndrome: an exome-sequencing studyThe integration of autophagy and cellular trafficking pathways via RAB GAPsTBC1D9B functions as a GTPase-activating protein for Rab11a in polarized MDCK cellsA RabGAP regulates life-cycle duration via trimeric G-protein cascades in Dictyostelium discoideum.Identification of regions critical for the integrity of the TSC1-TSC2-TBC1D7 complexAMP-Activated Protein Kinase Regulates the Cell Surface Proteome and Integrin Membrane Traffic.Evi5 promotes collective cell migration through its Rab-GAP activity.GPR21 KO mice demonstrate no resistance to high fat diet induced obesity or improved glucose tolerance.Recessive Inactivating Mutations in TBCK, Encoding a Rab GTPase-Activating Protein, Cause Severe Infantile Syndromic Encephalopathy.Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7).EPI64B acts as a GTPase-activating protein for Rab27B in pancreatic acinar cellsEpigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFRAnkyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomesDissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3.Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy.MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma.TBC1D14 regulates autophagy via the TRAPP complex and ATG9 trafficHomozygous Truncating Variants in TBC1D23 Cause Pontocerebellar Hypoplasia and Alter Cortical Development.Molecular control of Rab activity by GEFs, GAPs and GDI.Role of Rab GTPases in the export trafficking of G protein-coupled receptors.Host Factors Involved in the Intracellular Movement of Bamboo mosaic virusRab GTPases and their interacting protein partners: Structural insights into Rab functional diversity.TLDc proteins: new players in the oxidative stress response and neurological disease.A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactomeCancer: Linking Powerhouses to Suicidal Bags.
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P2860
Illuminating the functional and structural repertoire of human TBC/RABGAPs.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Illuminating the functional and structural repertoire of human TBC/RABGAPs.
@en
Illuminating the functional and structural repertoire of human TBC/RABGAPs.
@nl
type
label
Illuminating the functional and structural repertoire of human TBC/RABGAPs.
@en
Illuminating the functional and structural repertoire of human TBC/RABGAPs.
@nl
prefLabel
Illuminating the functional and structural repertoire of human TBC/RABGAPs.
@en
Illuminating the functional and structural repertoire of human TBC/RABGAPs.
@nl
P2093
P356
P1476
Illuminating the functional and structural repertoire of human TBC/RABGAPs
@en
P2093
Katja T Koessmeier
M Reza Ahmadian
Marieke A M Frasa
P2888
P356
10.1038/NRM3267
P577
2012-01-18T00:00:00Z