Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor.
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Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTsAptamer Displacement Screen for Flaviviral RNA Methyltransferase Inhibitors.Dietary compound isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation.Design, synthesis and biological evaluation of 4-amino-N- (4-aminophenyl)benzamide analogues of quinoline-based SGI-1027 as inhibitors of DNA methylation.Specific inhibition of one DNMT1-including complex influences tumor initiation and progression.Specific Inhibition of DNMT3A/ISGF3γ Interaction Increases the Temozolomide Efficiency to Reduce Tumor GrowthInhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes.Epigenetic therapy of hematological malignancies: where are we now?Rationalization of activity cliffs of a sulfonamide inhibitor of DNA methyltransferases with induced-fit docking.Developmental DNA methyltransferase inhibitors in the treatment of gynecologic cancers.The potential role of in silico approaches to identify novel bioactive molecules from natural resources.Docking of a novel DNA methyltransferase inhibitor identified from high-throughput screening: insights to unveil inhibitors in chemical databases.Theoretical study of methyl group transfer assisted by proton transfer reaction in the N-acylated imidates.Procaine is a specific DNA methylation inhibitor with anti-tumor effect for human gastric cancer.Toward drug repurposing in epigenetics: olsalazine as a hypomethylating compound active in a cellular context.Specific inhibition of DNMT1/CFP1 reduces cancer phenotypes and enhances chemotherapy effectiveness.Ensemble-Based Virtual Screening and Experimental Validation of Inhibitors Targeting a Novel Site of Human DNMT1.Inhibitors of DNA Methyltransferases From Natural Sources: A Computational Perspective
P2860
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P2860
Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor.
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article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Molecular modeling of inhibito ...... ry of a novel DNMT1 inhibitor.
@en
type
label
Molecular modeling of inhibito ...... ry of a novel DNMT1 inhibitor.
@en
prefLabel
Molecular modeling of inhibito ...... ry of a novel DNMT1 inhibitor.
@en
P2093
P2860
P1476
Molecular modeling of inhibito ...... ry of a novel DNMT1 inhibitor.
@en
P2093
Jakyung Yoo
Joo Hee Kim
José L Medina-Franco
Keith D Robertson
P2860
P304
P356
10.1016/B978-0-12-398312-1.00008-1
P577
2012-01-01T00:00:00Z