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The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancerNovel Molecular Markers for Breast CancerCurrent Medical Treatment of Patients with Non-Colorectal Liver Metastases: Primary Tumor Breast CancerTargeting CDK6 in cancer: State of the art and new insightsThe other side of the coin: the tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND-CDK4/6-RB axisCoordinating cell proliferation and differentiation: Antagonism between cell cycle regulators and cell type-specific gene expressionTargeted Therapies for Brain Metastases from Breast CancerTargeting the cyclin-dependent kinases (CDK) 4/6 in estrogen receptor-positive breast cancersPalbociclib: A New Option for Front-Line Treatment of Metastatic, Hormone Receptor-Positive, HER2-Negative Breast CancerFOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathwaysFolate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migrationPolymorphisms of microRNA target genes IL12B, INSR, CCND1 and IL10 in gastric cancer.Aspirin regulation of c-myc and cyclinD1 proteins to overcome tamoxifen resistance in estrogen receptor-positive breast cancer cells.Interactions between polymorphisms in the 3'untranslated region of the cyclin dependent kinase 6 gene and the human papillomavirus infection, and risk of cervical precancerous lesions.Cyclin D activates the Rb tumor suppressor by mono-phosphorylationBreast Cancer Update 2014 - Focus on the Patient and the Tumour.First-in-Class CDK4/6 Inhibitor Palbociclib Could Usher in a New Wave of Combination Therapies for HR+, HER2- Breast Cancer.Wenyang Huazhuo Tongluo formula, a Chinese herbal decoction, improves skin fibrosis by promoting apoptosis and inhibiting proliferation through down-regulation of survivin and cyclin D1 in systemic sclerosis.CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive RhabdomyosarcomaThe CDK4/CDK6 inhibitor PD0332991 paradoxically stabilizes activated cyclin D3-CDK4/6 complexes.Adenosine Attenuates Human Coronary Artery Smooth Muscle Cell Proliferation by Inhibiting Multiple Signaling Pathways That Converge on Cyclin D.Phospho-T356RB1 predicts survival in HPV-negative squamous cell carcinoma of the head and neck.Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinomaScreening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinomaDual function of MDM2 and MDMX toward the tumor suppressors p53 and RB.Aberrant expression of cyclin D1 in cancer.The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations.The potential role of PD0332991 (Palbociclib) in the treatment of multiple myeloma.Palbociclib: first global approval.Emerging therapeutic targets for the treatment of human acute myeloid leukemia (part 1) - gene transcription, cell cycle regulation, metabolism and intercellular communication.DNA methylation of tumor suppressor protein-coding and non-coding genes in multiple myeloma.CDK6-a review of the past and a glimpse into the future: from cell-cycle control to transcriptional regulation.CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation.CDK4/6 Inhibitor PD0332991 in Glioblastoma Treatment: Does It Have a Future?The roles and therapeutic potential of cyclin-dependent kinases (CDKs) in sarcoma.Targeting the KRAS variant for treatment of non-small cell lung cancer: potential therapeutic applications.Oncogenic KRAS-associated gene signature defines co-targeting of CDK4/6 and MEK as a viable therapeutic strategy in colorectal cancer.Platinum-zoledronate complex blocks gastric cancer cell proliferation by inducing cell cycle arrest and apoptosis.Cyclin-Dependent Kinase Inhibitors for the Treatment of Breast Cancer: Past, Present, and Future.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Signaling through cyclin D-dependent kinases.
@en
type
label
Signaling through cyclin D-dependent kinases.
@en
prefLabel
Signaling through cyclin D-dependent kinases.
@en
P2860
P356
P1433
P1476
Signaling through cyclin D-dependent kinases.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2013.137
P407
P577
2013-05-06T00:00:00Z
P5875
P6179
1041588704