Nucleic acid catalysis: metals, nucleobases, and other cofactors.
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Thirty-five years of research into ribozymes and nucleic acid catalysis: where do we stand today?227 Views of RNA: Is RNA Unique in Its Chemical Isomer Space?A Two-Metal-Ion-Mediated Conformational Switching Pathway for HDV Ribozyme ActivationA new heavy lanthanide-dependent DNAzyme displaying strong metal cooperativity and unrescuable phosphorothioate effect.Mg2+ ions: do they bind to nucleobase nitrogens?Looked at life from both sides nowComparison of structural, thermodynamic, kinetic and mass transport properties of Mg(2+) ion models commonly used in biomolecular simulations.Rational evolution of Cd2+-specific DNAzymes with phosphorothioate modified cleavage junction and Cd2+ sensing.Searching for a DNAzyme Version of the Leadzyme.Assessment of metal-assisted nucleophile activation in the hepatitis delta virus ribozyme from molecular simulation and 3D-RISM.Heavy atom labeled nucleotides for measurement of kinetic isotope effectsA DNAzyme requiring two different metal ions at two distinct sitesTwo Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.Effect of Zn2+ binding and enzyme active site on the transition state for RNA 2'-O-transphosphorylation interpreted through kinetic isotope effects.Force Field for Mg(2+), Mn(2+), Zn(2+), and Cd(2+) Ions That Have Balanced Interactions with Nucleic Acids.Ribozyme Catalysis with a Twist: Active State of the Twister Ribozyme in Solution Predicted from Molecular Simulation.Nucleic acid reactivity: challenges for next-generation semiempirical quantum models.Splitting a DNAzyme enables a Na+-dependent FRET signal from the embedded aptamer.DNA Catalysis: The Chemical Repertoire of DNAzymes.Divalent Metal Ion Activation of a Guanine General Base in the Hammerhead Ribozyme: Insights from Molecular Simulations.Applications and stereoselective syntheses of P-chirogenic phosphorus compounds.A decade of DNA-hybrid catalysis: from innovation to comprehension.Copper(II) and Zinc(II) Complexes of Conformationally Constrained Polyazamacrocycles as Efficient Catalysts for RNA Model Substrate Cleavage in Aqueous Solution at Physiological pH.Inverse thio effects in the hepatitis delta virus ribozyme reveal that the reaction pathway is controlled by metal ion charge density.Characterization of deoxyribozymes with site-specific oxidative cleavage activity against DNA obtained by in vitro selection.Multi-metal-dependent nucleic acid enzymes.Modulation of Ribozyme and Deoxyribozyme Activities Using Tetraalkylammonium Ions.Metals induce transient folding and activation of the twister ribozyme.Evidence of a General Acid/Base Catalysis Mechanism in the 8-17 DNAzyme.Divide and Control: Comparison of Split and Switch Hybridization Sensors.Phosphodiester models for cleavage of nucleic acids.A Selective Na(+) Aptamer Dissected by Sensitized Tb(3+) Luminescence.An Efficient Lanthanide-Dependent DNAzyme Cleaving 2'-5'-Linked RNA.A New Na(+)-Dependent RNA-Cleaving DNAzyme with over 1000-fold Rate Acceleration by Ethanol.Probing the effect of minor groove interactions on the catalytic efficiency of DNAzymes 8-17 and 10-23.Expanding biohybrid-mediated asymmetric catalysis into the realm of RNA.Multifunctional Poly-N -Isopropylacrylamide/DNAzyme Microgels as Highly Efficient and Recyclable Catalysts for BiosensingG-quadruplex–hemin DNAzyme molecular beacon probe for the detection of methamphetamine
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P2860
Nucleic acid catalysis: metals, nucleobases, and other cofactors.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
Nucleic acid catalysis: metals, nucleobases, and other cofactors.
@en
type
label
Nucleic acid catalysis: metals, nucleobases, and other cofactors.
@en
prefLabel
Nucleic acid catalysis: metals, nucleobases, and other cofactors.
@en
P2093
P2860
P356
P1433
P1476
Nucleic acid catalysis: metals, nucleobases, and other cofactors.
@en
P2093
Kory Plakos
Victoria J DeRose
W Luke Ward
P2860
P304
P356
10.1021/CR400476K
P577
2014-04-14T00:00:00Z
2014-04-23T00:00:00Z