Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo - Wikidata - thesis-toulmin - TriplyDB

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo

http://www.wikidata.org/entity/Q38966914

about

The associations between Parkinson's disease and cancer: the plot thickens The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease Adult hippocampal neurogenesis in Parkinson's disease: impact on neuronal survival and plasticity More than a Rumor Spreads in Parkinson's Disease Alpha-Synuclein Oligomers-Neurotoxic Molecules in Parkinson's Disease and Other Lewy Body Disorders Synaptopathies: synaptic dysfunction in neurological disorders - A review from students to students Seeking a mechanism for the toxicity of oligomeric α-synuclein Disease-toxicant interactions in Parkinson's disease neuropathology ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo.Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease.Higher levels of myelin phospholipids in brains of neuronal α-Synuclein transgenic mice precede myelin loss.Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson's Disease: Who's on First?Identification of synaptosomal proteins binding to monomeric and oligomeric α-synuclein.CSF proteins and resting-state functional connectivity in Parkinson disease.Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy.Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia Differential calcium alterations in animal models of neurodegenerative disease: Reversal by FK506 Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice.Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson's disease.Molecular neuropathology of the synapse in sheep with CLN5 Batten disease Network dysfunction in α-synuclein transgenic mice and human Lewy body dementia.Impaired intracellular trafficking defines early Parkinson's disease Insights on the interaction of alpha-synuclein and metals in the pathophysiology of Parkinson's disease.Structure, function and toxicity of alpha-synuclein: the Bermuda triangle in synucleinopathies.A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-Synuclein.Oligomeropathies and pathogenesis of Alzheimer and Parkinson's diseases.Calcium: Alpha-Synuclein Interactions in Alpha-Synucleinopathies.The Contribution of α-Synuclein Spreading to Parkinson's Disease Synaptopathy.Progress toward an integrated understanding of Parkinson's disease.α-synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease.Neuropeptide Treatment with Cerebrolysin Enhances the Survival of Grafted Neural Stem Cell in an α-Synuclein Transgenic Model of Parkinson's Disease.Impaired synaptic function is linked to cognition in Parkinson's disease.Active Immunization Against hIAPP Oligomers Ameliorates the Diabetes- Associated Phenotype in a Transgenic Mice Model.Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy.Rotenone and elevated extracellular potassium concentration induce cell-specific fibrillation of α-synuclein in axons of cholinergic enteric neurons in the guinea-pig ileum.Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice.Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy: translational implications for interventional therapies.Long-lasting pathological consequences of overexpression-induced α-synuclein spreading in the rat brain.

P2860

Q26778641-D709D419-8783-46FF-B6C3-1DBEECF19ABC Q26853537-531B41EF-A8B2-4C0F-B5D8-3831F515C499 Q26862840-FD158F15-1242-4736-8E38-2F5FFD47C3C1 Q28066571-E7372623-DBA1-44DA-908A-5556958B6D95 Q28067429-B9CECCB8-DF25-491C-B9A9-F30334F8BC02 Q28077671-86DA06EA-91CF-4FE3-8C30-F8391EAEF16F Q28080551-2532CA8F-EAC6-4F5A-8A47-995609A60150 Q29248297-E39B2DDE-7317-439C-A441-9B3B425BF354 Q30650119-80F3DDE8-FA71-4925-944D-55BD4FFB2A3A Q30795299-9B4C8C78-9A9A-4A45-BA51-C9EAEAEEB83D Q33647059-975719B2-21F9-4FC3-9AE5-8AA98FEBDB0A Q35412397-2CEE6E79-AECB-4FF6-926A-7693EA725EAC Q35557260-063AF7AA-6896-4054-8408-10120AF2F6AC Q35771985-6ED97A6F-BF45-496A-9F18-835A1C3A6290 Q35897340-B174F52E-26CA-416B-B7A9-EC73C0709274 Q36086721-EC000F40-D98A-4EAB-AE49-577D2435322F Q36146776-B0A0534A-DA12-4DF1-8817-38EFE84E78B6 Q36248908-EA149284-ED37-4DD3-8814-6906A133A397 Q36265332-0B59C5CB-D077-47B2-9690-1C78A48E00E9 Q36336723-8D0FF597-9F7B-4053-BD11-FEB6F1727440 Q36341812-B2B6A802-BA0A-4F62-8C14-0266CE545752 Q36410380-B2BEFC59-299D-481F-BB61-FEDF22EA0835 Q38256380-0EE3F501-0B3F-4F05-BE2F-605F7A6E21E5 Q38343049-ED7B1A30-D37E-4C94-8A87-3C285147B2D9 Q38550428-8A0F6D8E-654E-427A-8AD3-4CAF399D571F Q38741513-35F5335E-584A-4109-B5C3-BDC2FB214D51 Q38794219-25C63373-C637-48F7-A041-3EB319B911AB Q39075636-12272E39-5EE7-475F-A389-856DEEEE63B1 Q39108546-3E291F98-4255-461B-BC19-C5E773C9DEEA Q41012014-99A933D7-EA6B-43BA-AAEB-19194900B348 Q41117719-98E2F1CA-5472-435C-B8CE-DE515FF2D982 Q41832273-28040297-468F-448D-91E9-0D8BC6953001 Q42373778-0AD90A94-64B6-40DC-85DD-87A7C654D418 Q42630578-748DEE3A-31F4-4BEA-BAFF-FF9B8C7B7FE3 Q46124320-114CC1D9-A1CC-45FF-AD79-B8CBC8EE44BE Q46217157-BB9909BD-2508-4905-A2F5-CC3B0AEB81C1 Q46264316-001EE305-3769-473F-9593-460BD265D027 Q46362244-A98A1420-FD5E-43DB-AB12-0C103AC0567A Q47252776-7F1B2C6A-B664-4CDD-A40D-D576ABFB199A Q47547717-CE69FA2C-8C5F-4939-A69C-B3FAF899DB87

P2860

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo

http://www.wikidata.org/entity/Q38966914

description

2014 nî lūn-bûn

@nan

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

2014年论文

@zh

2014年论文

@zh-cn

name

Accumulation of oligomer-prone ...... neuronal degeneration in vivo

@en

type

label

Accumulation of oligomer-prone ...... neuronal degeneration in vivo

@en

prefLabel

Accumulation of oligomer-prone ...... neuronal degeneration in vivo

@en

P1433

Q38966914-2C8B2FD9-C75A-4807-AA69-43C0D8E3806F

P1476

Q38966914-16CB961D-C818-441A-8B85-EEA1D5B21587

P2093

Q38966914-14D0C7F0-019F-4426-AB11-ADB50FB799E1

Q38966914-5E0CAA11-D4A5-4224-8C4E-508BD4C93F8B

Q38966914-82DA665C-A7CE-4C30-B799-211B2E65C69F

Q38966914-8EBE8006-AE65-43E7-806F-74CD65A72475

Q38966914-914BDC7E-5704-4D38-8C34-11E746B11B91

Q38966914-96EEB534-10BE-4E6D-A9DD-F1C90FC7BF04

Q38966914-B8D9FE00-2219-4EAF-8B39-E3EDBB940F27

Q38966914-BD64A7FF-7852-4323-B9DC-AC39103B04D5

Q38966914-DEEF8E40-AE3E-4B43-B8E7-49B3821341BB

Q38966914-F26FEE62-FBCE-4EAE-940C-3436D3A9D5F2

P2860

Q38966914-07F7B40B-CCA2-42EF-AEDB-0EB351F7C606

Q38966914-0A1B5374-88FA-4F98-8881-154449B685C4

Q38966914-158EA575-3601-4D6B-8413-6EB6B543B236

Q38966914-16DDB4EB-698B-435C-8E7E-DB091BBAED6A

Q38966914-1743D2A4-4997-418B-BC09-8EB0AF5EA7DD

Q38966914-1CAB9D2F-97EE-4D59-98A9-B669A2180301

Q38966914-1E4334BD-70CE-4C89-AC81-AEF3F9A7F8CE

Q38966914-227468E1-975F-46A9-8BD6-864B23E3B01B

Q38966914-2AD69DD0-BF73-4B3C-A7FA-7DF524217430

Q38966914-2F21D5B8-D101-4C5D-870E-2D255C079B6E

P304

Q38966914-48C50F45-B49F-4472-AAB2-6A304C10A102

P31

Q38966914-2B90C894-C18F-4C66-883F-E707BE2C6318

P356

Q38966914-9C89A8F8-F8E2-4536-821C-4DDDDA60255C

P407

Q38966914-30C80A61-355E-484F-9C3A-DB58CC379CB9

P433

Q38966914-45D02ED0-9140-4D52-A47A-D2AF3CE9B220

P478

Q38966914-608F871F-AA9F-4996-8F03-745503651E34

P50

Q38966914-0474FEE8-A9A3-44DC-AFE9-7305C1A0E41A

Q38966914-5AD57019-A6BC-40A9-B7FB-58A4C1947656

Q38966914-7C64ECAB-DFE4-4F9A-B91E-24E4314F2D0A

Q38966914-AA71C6A8-FD3B-4AE2-A70A-384AA62E8513

Q38966914-CBA0576B-4580-4B9A-8DAA-DCBCC6B27951

P577

Q38966914-1722A629-A325-45EF-A0A2-2638E809B56D

P5875

Q38966914-D5E22CEE-A93D-4096-B6D1-F852061371E6

P698

Q38966914-2CF10D47-5275-4DE7-B3A6-C462FBDF1C63

P921

Q38966914-2610E398-F55D-4A6C-B149-B98658B60DE2

P932

Q38966914-4E64AF07-95BD-4AC3-9C02-AE8B54E2B5D7

P356

P1433

P1476

Accumulation of oligomer-prone ...... neuronal degeneration in vivo

@en

P2093

Anthony Adame

http://www.w3.org/2001/XMLSchema#string

Beate Winner

http://www.w3.org/2001/XMLSchema#string

Cassia R Overk

http://www.w3.org/2001/XMLSchema#string

Christina Patrick

http://www.w3.org/2001/XMLSchema#string

Fred H Gage

http://www.w3.org/2001/XMLSchema#string

Juan Gerez

http://www.w3.org/2001/XMLSchema#string

Jürgen Winkler

http://www.w3.org/2001/XMLSchema#string

Margarita Trejo-Morales

http://www.w3.org/2001/XMLSchema#string

Michael Mante

http://www.w3.org/2001/XMLSchema#string

Poul H Jensen

http://www.w3.org/2001/XMLSchema#string

P2860

The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia

Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model.

Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro

Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities

The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

Alpha-synuclein in Lewy bodies

Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice

The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins

P304

1496-1513

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/BRAIN/AWU057

http://www.w3.org/2001/XMLSchema#string

P407

P433

Pt 5

http://www.w3.org/2001/XMLSchema#string

P478

137

http://www.w3.org/2001/XMLSchema#string

P50

Eliezer Masliah

Edward Rockenstein

P577

2014-03-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

261067241

http://www.w3.org/2001/XMLSchema#string

P698

24662516

http://www.w3.org/2001/XMLSchema#string

P921

P932

3999721

http://www.w3.org/2001/XMLSchema#string