Telomeres in cancer: tumour suppression and genome instability.
about
The DDR at telomeres lacking intact shelterin does not require substantial chromatin decompaction.Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism.The essential kinase ATR: ensuring faithful duplication of a challenging genome.Double-stranded telomeric DNA binding proteins: Diversity matters.Convergent adaptation of cellular machineries in the evolution of large body masses and long life spans.RNA Binding Proteins and Genome Integrity.Chromosomally Integrated Human Herpesvirus 6: Models of Viral Genome Release from the Telomere and Impacts on Human Health.Scattered genomic amplification in dedifferentiated liposarcoma.Aging: Molecular Pathways and Implications on the Cardiovascular System.The Role of Pontin and Reptin in Cellular Physiology and Cancer Etiology.The Retinoblastoma (RB) Tumor Suppressor: Pushing Back against Genome Instability on Multiple Fronts.Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity.Biological and clinical implications of telomere dysfunction in myeloid malignancies.Machine Learning for Nuclear Mechano-Morphometric Biomarkers in Cancer Diagnosis.Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis.The global role for Cdc13 and Yku70 in preventing telomere resection across the genome.Chromothripsis 18 in multiple myeloma patient with rapid extramedullary relapse.Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data.Attachment and telomere length: more evidence for psychobiological connections between close relationships, health, and aging.Mild Telomere Dysfunction as a Force for Altering the Adaptive Potential of Subtelomeric Genes.Bleomycin-induced chromosomal damage and shortening of telomeres in peripheral blood lymphocytes of incident cancer patients.Leukocyte telomere length in relation to risk of lung adenocarcinoma incidence: Findings from the Singapore Chinese Health Study.LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast.Caught with One's Zinc Fingers in the Genome Integrity Cookie Jar.Simple Detection of Telomere Fusions in Pancreatic Cancer, Intraductal Papillary Mucinous Neoplasm, and Pancreatic Cyst Fluid.Dysfunctional telomeres and hematological disorders.Telomere length in poor-risk chronic lymphocytic leukemia: associations with disease characteristics and outcome.Telomere Length Dynamics and the Evolution of Cancer Genome Architecture.Maternal Inheritance of a Single Somatic Animal Cell Displayed by the Bacteriocyte in the Whitefly Bemisia tabaci.53BP1 can limit sister-chromatid rupture and rearrangements driven by a distinct ultrafine DNA bridging-breakage process.Hiding in Plain Sight: Rediscovering the Importance of Noncoding RNA in Human Malignancy.Reconstructing the molecular life history of gliomas.The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils.Genetic instability and recurrent MYC amplification in ALK-translocated NSCLC; a central role of TP53 mutations.Beginning at the ends: telomeres and human disease.Acute telomere deprotection prevents ongoing BFB cycles and rampant instability in p16INK4a-deficient epithelial cells.Short- and long-term evolution in our arms race with cancer: Why the war on cancer is winnable.Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cellsDDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint SignalingPatterns and mechanisms of structural variations in human cancer
P2860
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P2860
Telomeres in cancer: tumour suppression and genome instability.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Telomeres in cancer: tumour suppression and genome instability.
@en
Telomeres in cancer: tumour suppression and genome instability.
@nl
type
label
Telomeres in cancer: tumour suppression and genome instability.
@en
Telomeres in cancer: tumour suppression and genome instability.
@nl
prefLabel
Telomeres in cancer: tumour suppression and genome instability.
@en
Telomeres in cancer: tumour suppression and genome instability.
@nl
P2860
P356
P1476
Telomeres in cancer: tumour suppression and genome instability.
@en
P2860
P2888
P304
P356
10.1038/NRM.2016.171
P577
2017-01-18T00:00:00Z