Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer. - Wikidata - thesis-toulmin - TriplyDB

Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer.

Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer.

http://www.wikidata.org/entity/Q39126232

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Targeting DNA Damage Response in the Radio(Chemo)therapy of Non-Small Cell Lung Cancer Structural polymorphism in the N-terminal oligomerization domain of NPM1 Tumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage Response Systemic DNA damage responses in aging and diseases DNA Damage: From Chronic Inflammation to Age-Related Deterioration DNA Damage Response and Autophagy: A Meaningful Partnership BRCA1 and Oxidative Stress Regulation and roles of Cdc7 kinase under replication stress.Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans.Senescence and apoptosis: dueling or complementary cell fates?Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation Clonal heterogeneity of lymphoid malignancies correlates with poor prognosis.Tug of war between survival and death: exploring ATM function in cancer.DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.Radiotherapy-induced plasticity of prostate cancer mobilizes stem-like non-adherent, Erk signaling-dependent cells Knockdown of CDK2AP1 in primary human fibroblasts induces p53 dependent senescence.Reactivation of epigenetically silenced miR-512 and miR-373 sensitizes lung cancer cells to cisplatin and restricts tumor growth.Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress.Molecular genetic response to varied wavelengths of light in Xiphophorus maculatus skin CHMP4C Disruption Sensitizes the Human Lung Cancer Cells to Irradiation.Role of p14ARF-HDM2-p53 axis in SOX6-mediated tumor suppression p19(Arf) is required for the cellular response to chronic DNA damage Dynamic alterations of bone marrow cytokine landscape of myelodysplastic syndromes patients treated with 5-azacytidine.Regulation of the MDM2-p53 pathway by the nucleolar protein CSIG in response to nucleolar stress.The Mre11 complex suppresses oncogene-driven breast tumorigenesis and metastasis.Inflammation, DNA Damage, Helicobacter pylori and Gastric Tumorigenesis.Inhibition of GOT1 sensitizes colorectal cancer cells to 5-fluorouracil.ARF Confers a Context-Dependent Response to Chemotherapy in Muscle-Invasive Bladder Cancer Genetic Variability as a Regulator of TLR4 and NOD Signaling in Response to Bacterial Driven DNA Damage Response (DDR) and Inflammation: Focus on the Gastrointestinal (GI) Tract.Repression of phosphoglycerate dehydrogenase sensitizes triple-negative breast cancer to doxorubicin.Suppressor of cytokine signaling 1-dependent regulation of the expression and oncogenic functions of p21(CIP1/WAF1) in the liver.Haploinsufficiency of the E3 ubiquitin-protein ligase gene TRIP12 causes intellectual disability with or without autism spectrum disorders, speech delay, and dysmorphic features.Emerging power of proteomics for delineation of intrinsic tumor subtypes and resistance mechanisms to anti-cancer therapies.Mechanisms of p53 Functional De-Regulation: Role of the IκB-α/p53 Complex TRIP12 as a mediator of human papillomavirus/p16-related radiation enhancement effects.Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation.Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.ATM: An unexpected tumor-promoting factor in HER2-expressing tumors WWOX modulates the ATR-mediated DNA damage checkpoint response MKK7 and ARF: new players in the DNA damage response scenery.

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Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer.

http://www.wikidata.org/entity/Q39126232

description

2013 nî lūn-bûn

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2013年论文

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name

Functional interplay between t ...... essor protein in human cancer.

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Functional interplay between t ...... essor protein in human cancer.

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Functional interplay between t ...... essor protein in human cancer.

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Functional interplay between t ...... essor protein in human cancer.

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Functional interplay between t ...... essor protein in human cancer.

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Functional interplay between t ...... essor protein in human cancer.

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Nature Cell Biology

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Functional interplay between t ...... essor protein in human cancer.

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Apostolos Klinakis

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Athanassios Kotsinas

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Ayguel Dereli-Oz

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Dimitris Kletsas

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George Papafotiou

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Georgia Velimezi

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Ines Orsolic

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Ioannis S Pateras

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Kostas Evangelou

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Maciej Kocylowski

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Hallmarks of Cancer: The Next Generation

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Directed proteomic analysis of the human nucleolus

Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells

Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

N-terminal polyubiquitination and degradation of the Arf tumor suppressor

The DNA-damage response in human biology and disease

The combined status of ATM and p53 link tumor development with therapeutic response

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967-977

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10.1038/NCB2795

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8

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15

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Konstantinos Vougas

Sinisa Volarevic

Jiřina Bártková

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2013-07-14T00:00:00Z

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249320302

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