Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells.
about
Pancreatic regulation of glucose homeostasisSignaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cellsConformational states of syntaxin-1 govern the necessity of N-peptide binding in exocytosis of PC12 cells and Caenorhabditis elegansMunc18b is a major mediator of insulin exocytosis in rat pancreatic β-cellsInsulin secretion from beta cells in intact mouse islets is targeted towards the vasculature.Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodiesDoc2b enrichment enhances glucose homeostasis in mice via potentiation of insulin secretion and peripheral insulin sensitivityMunc18b Increases Insulin Granule Fusion, Restoring Deficient Insulin Secretion in Type-2 Diabetes Human and Goto-Kakizaki Rat Islets with Improvement in Glucose Homeostasis.Contact-induced clustering of syntaxin and munc18 docks secretory granules at the exocytosis site.Calcium current inactivation rather than pool depletion explains reduced exocytotic rate with prolonged stimulation in insulin-secreting INS-1 832/13 cells.Syntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells.Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells.Albiglutide: a new GLP-1 receptor agonist for the treatment of type 2 diabetes.Clinical pharmacology of albiglutide, a GLP-1 receptor agonist.Role of vesicle-associated membrane protein 2 in exocytosis of glucagon-like peptide-1 from the murine intestinal L cell.Exocyst sec5 regulates exocytosis of newcomer insulin granules underlying biphasic insulin secretion.Munc18c mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose stimulated insulin secretion in human pancreatic beta-cells.Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets.A Spatial Model of Insulin-Granule Dynamics in Pancreatic β-Cells.The dynamic plasticity of insulin production in β-cells.Rab5 is critical for SNAP23 regulated granule-granule fusion during compound exocytosis.Abnormal Rab11-Rab8-vesicles cluster in enterocytes of patients with microvillus inclusion disease.Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.Recent new insights into the role of SNARE and associated proteins in insulin granule exocytosis.Synaptotagmin isoforms confer distinct activation kinetics and dynamics to chromaffin cell granules.Syntaxin-4 mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose-stimulated insulin secretion in human pancreatic beta cells.Syntaxin 2 Acts as Inhibitory SNARE for Insulin Granule Exocytosis.New Roles of Syntaxin-1A in Insulin Granule Exocytosis and Replenishment.
P2860
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P2860
Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Syntaxin-3 regulates newcomer ...... sion in pancreatic beta cells.
@en
Syntaxin-3 regulates newcomer ...... sion in pancreatic beta cells.
@nl
type
label
Syntaxin-3 regulates newcomer ...... sion in pancreatic beta cells.
@en
Syntaxin-3 regulates newcomer ...... sion in pancreatic beta cells.
@nl
prefLabel
Syntaxin-3 regulates newcomer ...... sion in pancreatic beta cells.
@en
Syntaxin-3 regulates newcomer ...... sion in pancreatic beta cells.
@nl
P2093
P2860
P1433
P1476
Syntaxin-3 regulates newcomer ...... sion in pancreatic beta cells.
@en
P2093
H Y Gaisano
P2860
P2888
P304
P356
10.1007/S00125-012-2757-0
P577
2012-11-07T00:00:00Z