Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization.

Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization.

Item
http://www.wikidata.org/entity/Q39503640
RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D.Design, synthesis, and biological evaluation of stable colchicine binding site tubulin inhibitors as potential anticancer agents.Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterol.Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytesOrally bioavailable tubulin antagonists for paclitaxel-refractory cancer.New substituted 4H-chromenes as anticancer agents.Discovery of 4-Aryl-2-benzoyl-imidazoles as tubulin polymerization inhibitor with potent antiproliferative properties.Synergistic combination of novel tubulin inhibitor ABI-274 and vemurafenib overcome vemurafenib acquired resistance in BRAFV600E melanoma.In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland.Discovery of novel 2-aryl-4-benzoyl-imidazole (ABI-III) analogues targeting tubulin polymerization as antiproliferative agents.3-substituted 2-phenylimidazo[2,1-b]benzothiazoles: synthesis, anticancer activity, and inhibition of tubulin polymerization.Synthesis and Structure-Activity Relationships of Imidazole-Coumarin Conjugates against Hepatitis C Virus.Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.Nickel-catalyzed decarboxylative acylation of heteroarenes by sp2 C-H functionalization.
P2860

Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization.

Item
http://www.wikidata.org/entity/Q39503640
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
Synthesis and antiproliferativ ...... geting tubulin polymerization.
@en
Synthesis and antiproliferativ ...... geting tubulin polymerization.
@nl
type
label
Synthesis and antiproliferativ ...... geting tubulin polymerization.
@en
Synthesis and antiproliferativ ...... geting tubulin polymerization.
@nl
prefLabel
Synthesis and antiproliferativ ...... geting tubulin polymerization.
@en
Synthesis and antiproliferativ ...... geting tubulin polymerization.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Synthesis and antiproliferativ ...... geting tubulin polymerization.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932