Kinetic studies of the Arf activator Arno on model membranes in the presence of Arf effectors suggest control by a positive feedback loop.
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Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factorsArf GTPase regulation through cascade mechanisms and positive feedback loopsRegulation of small GTPases by GEFs, GAPs, and GDIsRegulating the large Sec7 ARF guanine nucleotide exchange factors: the when, where and how of activationGTPase networks in membrane trafficThe capping domain in RalF regulates effector functionsIntegrated Conformational and Lipid-Sensing Regulation of Endosomal ArfGEF BRAG2A Novel Membrane Sensor Controls the Localization and ArfGEF Activity of Bacterial RalFAldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution.ARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartmentThe Drosophila Arf1 homologue Arf79F is essential for lamellipodium formation.Chlamydia Hijacks ARF GTPases To Coordinate Microtubule Posttranslational Modifications and Golgi Complex PositioningEFA6 controls Arf1 and Arf6 activation through a negative feedback loop.Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegansSalmonella virulence effector SopE and Host GEF ARNO cooperate to recruit and activate WAVE to trigger bacterial invasion.The cytohesin coiled-coil domain interacts with threonine 276 to control membrane association.Stepping stone: a cytohesin adaptor for membrane cytoskeleton restraint in the syncytial Drosophila embryoShigella flexneri regulation of ARF6 activation during bacterial entry via an IpgD-mediated positive feedback loop.ARF family G proteins and their regulators: roles in membrane transport, development and disease.The small G protein Arl1 directs the trans-Golgi-specific targeting of the Arf1 exchange factors BIG1 and BIG2.PH Domain-Arf G Protein Interactions Localize the Arf-GEF Steppke for Cleavage Furrow Regulation in Drosophila.Function and mode of action of cytohesins in the epidermal growth factor pathway in colorectal cancer cellsArf6 coordinates actin assembly through the WAVE complex, a mechanism usurped by Salmonella to invade host cells.Allosteric regulation of Arf GTPases and their GEFs at the membrane interface.Biochemical methods for studying kinetic regulation of Arf1 activation by Sec7.High yield production of myristoylated Arf6 small GTPase by recombinant N-myristoyl transferase.Inhibition of WAVE Regulatory Complex Activation by a Bacterial Virulence Effector Counteracts Pathogen PhagocytosisThe Arf GTPase-activating protein family is exploited by Salmonella enterica serovar Typhimurium to invade nonphagocytic host cells.Kinetics of interaction between ADP-ribosylation factor-1 (Arf1) and the Sec7 domain of Arno guanine nucleotide exchange factor, modulation by allosteric factors, and the uncompetitive inhibitor brefeldin A.Grp1 plays a key role in linking insulin signaling to glut4 recyclingGEF-effector interactions.Autoregulation of Sec7 Arf-GEF activity and localization by positive feedbackThe Sec7 Arf-GEF is recruited to the trans-Golgi network by positive feedback.A role for the vesicle-associated tubulin binding protein ARL6 (BBS3) in flagellum extension in Trypanosoma brucei.Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.GBF1 and Arf1 function in vesicular trafficking, lipid homoeostasis and organelle dynamics.The ARF guanine nucleotide exchange factor GBF1 is targeted to Golgi membranes through a PIP-binding domain.Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors.Arf6 negatively controls the rapid recycling of the β2 adrenergic receptor.ARF1 and ARF6 regulate recycling of GRASP/Tamalin and the Rac1-GEF Dock180 during HGF-induced Rac1 activation.
P2860
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P2860
Kinetic studies of the Arf activator Arno on model membranes in the presence of Arf effectors suggest control by a positive feedback loop.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Kinetic studies of the Arf act ...... l by a positive feedback loop.
@en
Kinetic studies of the Arf act ...... l by a positive feedback loop.
@nl
type
label
Kinetic studies of the Arf act ...... l by a positive feedback loop.
@en
Kinetic studies of the Arf act ...... l by a positive feedback loop.
@nl
prefLabel
Kinetic studies of the Arf act ...... l by a positive feedback loop.
@en
Kinetic studies of the Arf act ...... l by a positive feedback loop.
@nl
P2093
P2860
P356
P1476
Kinetic studies of the Arf act ...... l by a positive feedback loop.
@en
P2093
Bruno Antonny
Catherine L Jackson
Danièle Stalder
Eric Macia
Hélène Barelli
Romain Gautier
P2860
P304
P356
10.1074/JBC.M110.145532
P407
P577
2010-11-30T00:00:00Z