Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2).
about
Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cellsMembrane transport of camptothecin: facilitation by human P-glycoprotein (ABCB1) and multidrug resistance protein 2 (ABCC2)Single Nucleotide Polymorphisms in Cellular Drug Transporters Are Associated with Intolerance to Antiretroviral Therapy in Brazilian HIV-1 Positive IndividualsTargeting multidrug resistance in cancerDrug resistance in brain diseases and the role of drug efflux transporters.A neuroprotective mechanism of YGY-E in cerebral ischemic injury in rats.Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effectsIntestinal absorption of novel-dipeptide prodrugs of saquinavir in rats.Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitorPharmacologic and nonpharmacologic options for the management of HIV infection during pregnancy.P glycoprotein in human immunodeficiency virus type 1 infection and therapy.Practical aspects of transporter model systems: a case study involving SQV.The implications of P-glycoprotein in HIV: friend or foe?Drug-drug interactions involving membrane transporters in the human kidney.Stronger activity of human immunodeficiency virus type 1 protease inhibitors against clinical isolates of Plasmodium vivax than against those of P. falciparum.Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment.Investigation of the micellar effect of pluronic P85 on P-glycoprotein inhibition: cell accumulation and equilibrium dialysis studies.Protective roles of Gadd45 and MDM2 in blueberry anthocyanins mediated DNA repair of fragmented and non-fragmented DNA damage in UV-irradiated HepG2 cells.Interactions of pluronic block copolymers on P-gp efflux activity: experience with HIV-1 protease inhibitors.ABC transporters and isothiocyanates: potential for pharmacokinetic diet-drug interactions.ABC transporters in human lymphocytes: expression, activity and role, modulating factors and consequences for antiretroviral therapies.Prodrug and conjugate drug delivery strategies for improving HIV/AIDS therapy.Multidrug resistance associated proteins in multidrug resistance.Intestinal transporters for endogenic and pharmaceutical organic anions: the challenges of deriving in-vitro kinetic parameters for the prediction of clinically relevant drug-drug interactions.Importance of ABCC1 for cancer therapy and prognosis.Placental ABC Transporters: Biological Impact and Pharmaceutical Significance.Renal Drug Transporters and Drug Interactions.Mrp2 is involved in the efflux and disposition of fosinopril.Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux.Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir.Kinetic modelling of passive transport and active efflux of a fluoroquinolone across Caco-2 cells using a compartmental approach in NONMEM.Quantitative determination of the human MRP1 and MRP2 mRNA expression in FACS-sorted peripheral blood CD4+, CD8+, CD19+, and CD56+ cells.
P2860
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P2860
Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2).
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Direct evidence that saquinavi ...... anic anion transporter (MRP2).
@en
Direct evidence that saquinavir is transported by multidrug resistance-associated protein
@nl
type
label
Direct evidence that saquinavi ...... anic anion transporter (MRP2).
@en
Direct evidence that saquinavir is transported by multidrug resistance-associated protein
@nl
prefLabel
Direct evidence that saquinavi ...... anic anion transporter (MRP2).
@en
Direct evidence that saquinavir is transported by multidrug resistance-associated protein
@nl
P2093
P2860
P1476
Direct evidence that saquinavi ...... ganic anion transporter (MRP2)
@en
P2093
Angela Liu
Gregory C Williams
Gregory Knipp
P2860
P304
P356
10.1128/AAC.46.11.3456-3462.2002
P407
P577
2002-11-01T00:00:00Z