Norepinephrine promotes microglia to uptake and degrade amyloid beta peptide through upregulation of mouse formyl peptide receptor 2 and induction of insulin-degrading enzyme.
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Adrenergic regulation of innate immunity: a reviewBrain plasticity-based therapeuticsMechanisms of U87 astrocytoma cell uptake and trafficking of monomeric versus protofibril Alzheimer's disease amyloid-β proteinsNorepinephrine modulates the motility of resting and activated microglia via different adrenergic receptors.Norepinephrine: a neuromodulator that boosts the function of multiple cell types to optimize CNS performanceMolecular biology for formyl peptide receptors in human diseases.The Components of Flemingia macrophylla Attenuate Amyloid β-Protein Accumulation by Regulating Amyloid β-Protein Metabolic Pathway.Soluble beta amyloid evokes alteration in brain norepinephrine levels: role of nitric oxide and interleukin-1.The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain.Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease.Quercetin ameliorates Aβ toxicity in Drosophila AD model by modulating cell cycle-related protein expression.The influence of synaptic activity on neuronal health.Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?P2 receptors for extracellular nucleotides in the central nervous system: role of P2X7 and P2Y₂ receptor interactions in neuroinflammation.Neuroprotective roles of the P2Y(2) receptor.The role of Beta-adrenergic receptor blockers in Alzheimer's disease: potential genetic and cellular signaling mechanisms.Amyloid-clearing proteins and their epigenetic regulation as a therapeutic target in Alzheimer's disease.Impact of Insulin Degrading Enzyme and Neprilysin in Alzheimer's Disease Biology: Characterization of Putative Cognates for Therapeutic Applications.Role of norepinephrine in Aβ-related neurotoxicity: dual interactions with Tyr10 and SNK(26-28) of Aβ.Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system.New Insights into Epigenetic and Pharmacological Regulation of Amyloid-Degrading Enzymes.Insulin-degrading enzyme: new therapeutic target for diabetes and Alzheimer's disease?Targeting the D Series Resolvin Receptor System for the Treatment of Osteoarthritis Pain.Effects of ageing and experimental diabetes on insulin-degrading enzyme expression in male rat tissues.Aβ internalization by neurons and glia.Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine.A regulatory role for β-adrenergic receptors regarding the resolvin D1 (RvD1) pathway in the diabetic retina.The cerebellum in Alzheimer's disease: evaluating its role in cognitive decline.Localization of endogenous amyloid-β to the coeruleo-cortical pathway: consequences of noradrenergic depletion.Trigeminal, Visceral and Vestibular Inputs May Improve Cognitive Functions by Acting through the Locus Coeruleus and the Ascending Reticular Activating System: A New Hypothesis.Androgen alleviates neurotoxicity of β-amyloid peptide (Aβ) by promoting microglial clearance of Aβ and inhibiting microglial inflammatory response to Aβ.Stimulating the Activity of Amyloid-Beta Degrading Enzymes: A Novel Approach for the Therapeutic Manipulation of Amyloid-Beta Levels.β-Adrenergic modulation of spontaneous spatiotemporal activity patterns and synchrony in hyperexcitable hippocampal circuits.Role of catalpol in ameliorating the pathogenesis of experimental autoimmune encephalomyelitis by increasing the level of noradrenaline in the locus coeruleus.Perspectives in molecular imaging using staging biomarkers and immunotherapies in Alzheimer's disease.Enriched environment enhances β-adrenergic signaling to prevent microglia inflammation by amyloid-βInflammation: the link between comorbidities, genetics, and Alzheimer's diseaseSwitching of the Microglial Activation Phenotype Is a Possible Treatment for Depression Disorder
P2860
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P2860
Norepinephrine promotes microglia to uptake and degrade amyloid beta peptide through upregulation of mouse formyl peptide receptor 2 and induction of insulin-degrading enzyme.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Norepinephrine promotes microg ...... n of insulin-degrading enzyme.
@en
Norepinephrine promotes microg ...... n of insulin-degrading enzyme.
@nl
type
label
Norepinephrine promotes microg ...... n of insulin-degrading enzyme.
@en
Norepinephrine promotes microg ...... n of insulin-degrading enzyme.
@nl
prefLabel
Norepinephrine promotes microg ...... n of insulin-degrading enzyme.
@en
Norepinephrine promotes microg ...... n of insulin-degrading enzyme.
@nl
P2093
P921
P1476
Norepinephrine promotes microg ...... on of insulin-degrading enzyme
@en
P2093
Lihua Qian
Lingfei Ruan
Xiaolei Liu
P304
11848-11857
P356
10.1523/JNEUROSCI.2985-10.2010
P407
P50
P577
2010-09-01T00:00:00Z