about
Identification of SFRP1 as a candidate mediator of stromal-to-epithelial signaling in prostate cancerHypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturationGlucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expressionPathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situF2-isoprostanes as a biomarker of oxidative stress in the mouse bladder.Il-6 signaling between ductal carcinoma in situ cells and carcinoma-associated fibroblasts mediates tumor cell growth and migrationTranscriptional profiling of inductive mesenchyme to identify molecules involved in prostate development and diseaseA comprehensive approach toward novel serum biomarkers for benign prostatic hyperplasia: the MPSA Consortium.A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells.Directed differentiation of bone marrow derived mesenchymal stem cells into bladder urothelium.Endodermal origin of bladder trigone inferred from mesenchymal-epithelial interactionAndrogen regulated genes in human prostate xenografts in mice: relation to BPH and prostate cancer.Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activityDisruption of PPARgamma signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy.Recruitment of CD34(+) fibroblasts in tumor-associated reactive stroma: the reactive microvasculature hypothesis.TGF-β1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouse.Chronic cyclic bladder over distention up-regulates hypoxia dependent pathwaysExpression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progressionALCAM/CD166 is a TGF-β-responsive marker and functional regulator of prostate cancer metastasis to boneSurgical intervention for symptomatic benign prostatic hyperplasia is correlated with expression of the AP-1 transcription factor networkFunctional remodeling of benign human prostatic tissues in vivo by spontaneously immortalized progenitor and intermediate cellsStromal androgen receptor in prostate development and cancer.Expression of pleiotrophin in the prostate is androgen regulated and it functions as an autocrine regulator of mesenchyme and cancer associated fibroblasts and as a paracrine regulator of epithelia.Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networksRole of stroma in carcinogenesis of the prostate.Stretching fibroblasts remodels fibronectin and alters cancer cell migrationInhibition of NF-kappa B signaling restores responsiveness of castrate-resistant prostate cancer cells to anti-androgen treatment by decreasing androgen receptor-variant expression.PPARγ: a molecular link between systemic metabolic disease and benign prostate hyperplasia.Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion.Approaches to understanding the importance and clinical implications of peroxisome proliferator-activated receptor gamma (PPARgamma) signaling in prostate cancer.Directed differentiation of embryonic stem cells into bladder tissue.Molecular, cellular and developmental biology of urothelium as a basis of bladder regeneration.PPARγ isoforms differentially regulate metabolic networks to mediate mouse prostatic epithelial differentiation.Androgen hormone action in prostatic carcinogenesis: stromal androgen receptors mediate prostate cancer progression, malignant transformation and metastasis.NF-κB and androgen receptor variant expression correlate with human BPH progressionNfib Regulates Transcriptional Networks That Control the Development of Prostatic HyperplasiaBladder stromal loss of transforming growth factor receptor II decreases fibrosis after bladder obstructionIsolation and analysis of discreet human prostate cellular populationsNF-κB and androgen receptor variant 7 induce expression of SRD5A isoforms and confer 5ARI resistance.
P50
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P50
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hulumtues
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հետազոտող
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name
Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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type
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Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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Simon W. Hayward
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7102776230
P21
P31
P496
0000-0002-6059-6550