The human CK gene segment and the kappa deleting element are closely linked.
about
Bos taurus genome sequence reveals the assortment of immunoglobulin and surrogate light chain genes in domestic cattleReceptor selection in B and T lymphocytes.Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappaB cell development in mice that lack one or both immunoglobulin kappa light chain genes.Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in transAnalysis of expressed and non-expressed IGK locus rearrangements in chronic lymphocytic leukemia.B cell receptor light chain repertoires show signs of selection with differences between groups of healthy individuals and SLE patients.Immunoglobulin V gene expression in CD5 B-cell malignancies.Nucleotide sequence of the intron of the germline human kappa immunoglobulin gene connecting the J and C regions reveals a matrix association region (MAR) next to the enhancerThe germ-line counterpart of a non-VK sequence rearranged to JK1 in MOPC41 is located on mouse chromosome 6.Reciprocal recombination products of VK-JK joining reactions in human lymphoid cell lines.Induced rearrangement of kappa genes in the BLIN-1 human pre-B cell line correlates with germline J-C kappa and V kappa transcription.The kappa-deleting element. Germline and rearranged, duplicated and dispersed formsIdentification of a DNA segment exhibiting rearrangement modifying effects upon transgenic delta-deleting elements.Genomic organization and evolution of immunoglobulin kappa gene enhancers and kappa deleting element in mammals.Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus.Novel FISH probes designed to detect IGK-MYC and IGL-MYC rearrangements in B-cell lineage malignancy identify a new breakpoint cluster region designated BVR2.Linking of the human immunoglobulin VK and JKCK regions by chromosomal walking.A sequence homologous to kappa-deleting element is located 5' to the human JK locus.Deletion of human JK segments by site-specific recombination recognizing the conserved nonamer and heptamer sequences.The human kappa deleting element and the mouse recombining segment share DNA sequence homologyTransposition of human immunoglobulin V kappa genes within the same chromosome and the mechanism of their amplification.Immunoglobulin light chain (IgL) genes in zebrafish: Genomic configurations and inversional rearrangements between (V(L)-J(L)-C(L)) gene clusters.Rearrangement of mouse immunoglobulin kappa deleting element recombining sequence promotes immune tolerance and lambda B cell production.Ordered activation of the Ig lambda locus in Abelson B cell lines.Indications for peripheral light-chain revision and somatic hypermutation without a functional B-cell receptor in precursors of a composite diffuse large B-cell and Hodgkin's lymphoma.Immunoglobulin Gene Rearrangement and Expression in B-CLL.Heterogeneous breakpoints on the immunoglobulin genes are involved in fusion with the 5' region of BCL2 in B-cell tumors.
P2860
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P2860
The human CK gene segment and the kappa deleting element are closely linked.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
The human CK gene segment and the kappa deleting element are closely linked.
@en
type
label
The human CK gene segment and the kappa deleting element are closely linked.
@en
prefLabel
The human CK gene segment and the kappa deleting element are closely linked.
@en
P2860
P356
P1476
The human CK gene segment and the kappa deleting element are closely linked.
@en
P2093
P2860
P304
P356
10.1093/NAR/14.11.4591
P577
1986-06-01T00:00:00Z