Actin mutations in hypertrophic and dilated cardiomyopathy cause inefficient protein folding and perturbed filament formation.
about
Functional consequences of a mutation in an expressed human alpha-cardiac actin at a site implicated in familial hypertrophic cardiomyopathyMisfolded proteins partition between two distinct quality control compartmentsProteomic profiling of cardiac tissue by isolation of nuclei tagged in specific cell types (INTACT)Subdomain location of mutations in cardiac actin correlate with type of functional change.Caenorhabditis elegans chaperonin CCT/TRiC is required for actin and tubulin biogenesis and microvillus formation in intestinal epithelial cellsEffects of salvianolic Acid B on protein expression in human umbilical vein endothelial cellsChallenging muscle homeostasis uncovers novel chaperone interactions in Caenorhabditis elegansA Differentiation Transcription Factor Establishes Muscle-Specific Proteostasis in Caenorhabditis elegans.E101K and M123V alpha-cardiac actin gene mutations are not associated with cardiomyopathy in Iranian population.Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy.Molecular basis of hereditary cardiomyopathy: abnormalities in calcium sensitivity, stretch response, stress response and beyond.Conformational dynamics of actin: effectors and implications for biological function.Do cardiac actin mutations lead to altered actomyosin interactions?Using baculovirus/insect cell expressed recombinant actin to study the molecular pathogenesis of HCM caused by actin mutation A331PExpression of actin mutants to study their roles in cardiomyopathy.A novel approach to select differential pathways associated with hypertrophic cardiomyopathy based on gene co‑expression analysis.Genetic variations of α-cardiac actin and cardiac muscle LIM protein in hypertrophic cardiomyopathy in South IndiaDistortion of the Actin A-Triad Results in Contractile Disinhibition and Cardiomyopathy.Functional characterization of the human α-cardiac actin mutations Y166C and M305L involved in hypertrophic cardiomyopathy.TRiC/CCT chaperonins are essential for maintaining myofibril organization, cardiac physiological rhythm, and lifespan.Mammalian Actins: Isoform-Specific Functions and Diseases.Molecular mechanisms of disease-related human β-actin mutations p.R183W and p.E364K.Classifying Cardiac Actin Mutations Associated With Hypertrophic Cardiomyopathy.
P2860
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P2860
Actin mutations in hypertrophic and dilated cardiomyopathy cause inefficient protein folding and perturbed filament formation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Actin mutations in hypertrophi ...... perturbed filament formation.
@en
type
label
Actin mutations in hypertrophi ...... perturbed filament formation.
@en
prefLabel
Actin mutations in hypertrophi ...... perturbed filament formation.
@en
P2093
P50
P1433
P1476
Actin mutations in hypertrophi ...... perturbed filament formation.
@en
P2093
Anders D Børglum
Jens Mogensen
Melissa D Scott
Niels Gregersen
P2860
P304
P356
10.1111/J.1742-4658.2005.04630.X
P407
P577
2005-04-01T00:00:00Z