about
Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcriptionCompeting E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasmRegulation of dopaminergic transmission and cocaine reward by the Clock gene.A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivoObesity and metabolic syndrome in circadian Clock mutant miceRegulation of circadian behaviour and metabolism by synthetic REV-ERB agonistsSetting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteinsDisruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetesCircadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesisMolecular architecture of the mammalian circadian clockEmergence of noise-induced oscillations in the central circadian pacemakerBrain-specific rescue of Clock reveals system-driven transcriptional rhythms in peripheral tissueCrystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator ComplexCKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clockRole of the CLOCK protein in the mammalian circadian mechanismMolecular components of the circadian clock in mammalsClock controls circadian period in isolated suprachiasmatic nucleus neuronsPositional syntenic cloning and functional characterization of the mammalian circadian mutation tau.Coordinated transcription of key pathways in the mouse by the circadian clockMutagenesis and mapping of a mouse gene, Clock, essential for circadian behaviorMolecular components of the mammalian circadian clockCircadian clock mutation disrupts estrous cyclicity and maintenance of pregnancyBK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker outputThe gene for soluble N-ethylmaleimide sensitive factor attachment protein alpha is mutated in hydrocephaly with hop gait (hyh) micePhosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period lengthMop3 is an essential component of the master circadian pacemaker in mammalsMouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologiesCentral circadian control of female reproductive functionTranscriptional architecture and chromatin landscape of the core circadian clock in mammalsThe genetics of mammalian circadian order and disorder: implications for physiology and diseaseCentral and peripheral circadian clocks in mammalsMammalian circadian biology: elucidating genome-wide levels of temporal organizationCircadian integration of metabolism and energeticsThe meter of metabolism.The Xenopus clock gene is constitutively expressed in retinal photoreceptors.Xenobiotic metabolism in the fourth dimension: PARtners in time.Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathwayMaternal behavior modulates X-linked inheritance of behavioral coping in the defensive burying test.Mania-like behavior induced by disruption of CLOCKImpaired limbic gamma oscillatory synchrony during anxiety-related behavior in a genetic mouse model of bipolar mania
P50
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P50
description
forsker, University of Texas Southwestern Medical Center
@da
onderzoeker
@nl
researcher, University of Texas Southwestern Medical Center
@en
հետազոտող
@hy
name
Joseph S. Takahashi
@ast
Joseph S. Takahashi
@da
Joseph S. Takahashi
@de
Joseph S. Takahashi
@en
Joseph S. Takahashi
@es
Joseph S. Takahashi
@fo
Joseph S. Takahashi
@fr
Joseph S. Takahashi
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Joseph S. Takahashi
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Joseph S. Takahashi
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type
label
Joseph S. Takahashi
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Joseph S. Takahashi
@da
Joseph S. Takahashi
@de
Joseph S. Takahashi
@en
Joseph S. Takahashi
@es
Joseph S. Takahashi
@fo
Joseph S. Takahashi
@fr
Joseph S. Takahashi
@is
Joseph S. Takahashi
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Joseph S. Takahashi
@nb
prefLabel
Joseph S. Takahashi
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Joseph S. Takahashi
@da
Joseph S. Takahashi
@de
Joseph S. Takahashi
@en
Joseph S. Takahashi
@es
Joseph S. Takahashi
@fo
Joseph S. Takahashi
@fr
Joseph S. Takahashi
@is
Joseph S. Takahashi
@kl
Joseph S. Takahashi
@nb
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P1053
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