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Long-Range Regulation of V(D)J RecombinationThe role of CTCF in regulating V(D)J recombinationCRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci.RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin lociSilencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation.A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location.VH replacement in primary immunoglobulin repertoire diversification.Interpreting 4C-Seq data: how far can we go?CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation.Yin Yang 1 is a critical regulator of B-cell development4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments.Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasmsClose proximity to Igh is a contributing factor to AID-mediated translocations.Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombinationThe origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity.A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch RecombinationIdentification of multi-loci hubs from 4C-seq demonstrates the functional importance of simultaneous interactions.β-Catenin induces T-cell transformation by promoting genomic instability.MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection.A new take on v(d)j recombination: transcription driven nuclear and chromatin reorganization in rag-mediated cleavage.Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling.Molecular biology. Finding the right partner in a 3D genome.Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene.Breaking TADs: insights into hierarchical genome organization.It takes two: communication between homologous alleles preserves genomic stability during V(D)J recombination.The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation.Taking a break from the lab: can it really be done?Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus.Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.Equal opportunity for all.Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells.Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene.IL-7 functionally segregates the pro-B cell stage by regulating transcription of recombination mediators across cell cycle.Response to Casellas et al.The Conserved ATM Kinase RAG2-S365 Phosphorylation Site Limits Cleavage Events in Individual Cells Independent of Any Repair Defect.RAG Off-Target Activity Is in the Loop.Epigenetic ontogeny of the Igk locus during B cell development.
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