about
Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytesATP-binding cassette transporters, atherosclerosis, and inflammationCholesterol, inflammation and innate immunityInsulin and angiotensin II induce the translocation of scavenger receptor class B, type I from intracellular sites to the plasma membrane of adipocytes.Mild renal dysfunction and metabolites tied to low HDL cholesterol are associated with monocytosis and atherosclerosis.Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity.Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport.ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice.Cdkn2a is an atherosclerosis modifier locus that regulates monocyte/macrophage proliferation.HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.ATP-binding cassette transporter G1 and high-density lipoprotein promote endothelial NO synthesis through a decrease in the interaction of caveolin-1 and endothelial NO synthase.Disruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE(-/-) Mice.HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis.Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions.Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses.Cholesterol efflux: a novel regulator of myelopoiesis and atherogenesis.Understanding macrophage diversity at the ontogenic and transcriptomic levels.Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL.HIF-2α in Resting Macrophages Tempers Mitochondrial Reactive Oxygen Species To Selectively Repress MARCO-Dependent Phagocytosis.ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis.ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation.Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways.Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis.Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib.Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance.[Raising HDL-cholesterol: the future drug therapy for atherosclerosis?].ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain.Deficiency of ATP-binding cassette transporter B6 in megakaryocyte progenitors accelerates atherosclerosis in mice.Prevention of adipose tissue depletion during food deprivation in angiotensin type 2 receptor-deficient mice.Gender-related response of lipid metabolism to dietary fatty acids in the hamster.Maintenance of Macrophage Redox Status by ChREBP Limits Inflammation and Apoptosis and Protects against Advanced Atherosclerotic Lesion Formation.Inhibition of cholesteryl ester transfer protein by torcetrapib modestly increases macrophage cholesterol efflux to HDL.Liver X receptor α-dependent iron handling in M2 macrophages: The missing link between cholesterol and intraplaque hemorrhage?Pivotal Advance: Macrophages become resistant to cholesterol-induced death after phagocytosis of apoptotic cellsMacrophage Origin, Metabolic Reprogramming and IL-1 Signaling: Promises and Pitfalls in Lung CancerThe failure of torcetrapib: was it the molecule or the mechanism?Deficiency of angiotensin type 2 receptor rescues obesity but not hypertension induced by overexpression of angiotensinogen in adipose tissue[HDL and its transporters ABCA1 and ABCG1 regulate innate immunity and hematopoietic stem cell proliferation]
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
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Laurent Yvan-Charvet
@nl
Laurent Yvan-Charvet
@sl
P106
P21
P31
P496
0000-0002-7748-4942