The complex structure and function of Mediator.

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Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of Cyclin C-CDK8/19.The mediator complex in genomic and non-genomic signaling in cancer.Introduction to the Thematic Minireview Series: Chromatin and transcription

P2860

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P2860

The complex structure and function of Mediator.

Item

http://www.wikidata.org/entity/Q41596446

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2017 nî lūn-bûn

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2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

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2017年論文

@zh-tw

2017年论文

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2017年论文

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2017年论文

@zh-cn

name

The complex structure and function of Mediator.

@en

type

Item

label

The complex structure and function of Mediator.

@en

prefLabel

The complex structure and function of Mediator.

@en

P1476

The complex structure and function of Mediator.

@en

P2093

Dylan J Taatjes

http://www.w3.org/2001/XMLSchema#string

Thomas M Harper

http://www.w3.org/2001/XMLSchema#string

P275

Creative Commons Attribution

P2860

Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies

Subunit architecture and functional modular rearrangements of the transcriptional mediator complex

The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder

The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator

Mutations in the RNA polymerase II transcription machinery suppress the hyperrecombination mutant hpr1 delta of Saccharomyces cerevisiae

General requirement for RNA polymerase II holoenzymes in vivo

TFIID and human mediator coactivator complexes assemble cooperatively on promoter DNA

Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation

Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways

Mediator kinase module and human tumorigenesis

P31

scholarly article

review article

P356

10.1074/JBC.R117.794438

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P407

English

P577

2017-09-14T00:00:00Z

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2018-09-07T00:00:00Z

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P698

28912271

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P921

nuclear protein

peptide

transport protein

RNA nucleotidyltransferases

macromolecular substances

Anzim

P932

6130968

http://www.w3.org/2001/XMLSchema#string

The complex structure and function of Mediator.

about

P2860

P2860

The complex structure and function of Mediator.

description

name

type

label

prefLabel

P1433

P1476

P2093

P275

P2860

P31

P356

P407

P577

P698

P921

P932

P356

P1433

P1476

P2093

P275

P2860

P31

P356

P407

P577

P698

P921

P932